Science | Nature | Cell | View More
Natural Products
Daphylloside
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Daphylloside
Price: $318 / 10mg
CAS No.: 14260-99-2
Catalog No.: CFN99468
Molecular Formula: C19H26O12
Molecular Weight: 446.4 g/mol
Purity: >=98%
Type of Compound: Iridoids
Physical Desc.: Powder
Source: The leaves of Daphniphyllum macropodum
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $206.7 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Uniwersytet Gdański (Poland)
  • S.N.D.T. Women's University (India)
  • Yale University (USA)
  • Charles Sturt University (Denmark)
  • University of Helsinki (Finland)
  • Heidelberg University (Germany)
  • Sanford Burnham Medical Researc... (USA)
  • The Institute of Cancer Research (United Kingdom)
  • Medical University of Gdansk (Poland)
  • Florida International University (USA)
  • Harvard University (USA)
  • More...
Package
Featured Products
Momordicoside K

Catalog No: CFN92305
CAS No: 81348-84-7
Price: $ / mg
Oxymatrine

Catalog No: CFN99805
CAS No: 16837-52-8
Price: $40/20mg
Kirenol

Catalog No: CFN98867
CAS No: 52659-56-0
Price: $50/20mg
Biatractylolide

Catalog No: CFN95205
CAS No: 182426-37-5
Price: $268/10mg
11-Oxomogroside III

Catalog No: CFN92192
CAS No: 952481-53-7
Price: $318/10mg
Intermedine

Catalog No: CFN00285
CAS No: 10285-06-0
Price: $ /
Icariin

Catalog No: CFN99554
CAS No: 489-32-7
Price: $30/20mg
6-Methoxyluteolin

Catalog No: CFN92706
CAS No: 520-11-6
Price: $268/20mg
Alpha-pinene

Catalog No: CFN93285
CAS No: 80-56-8
Price: $30/20mg
6''-O-Malonylgenistin

Catalog No: CFN90631
CAS No: 51011-05-3
Price: $348/5mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Daphylloside and asperuloside can be suggested as endoplasmic reticulum stress regulators.
In vitro:
Vietnam Journal of Chemistry, 2015, 53(2e).
Iridoid glycosides from Morinda tomentosa and their endoplasmic reticulum stress modulation activity[Reference: WebLink]
Three iridoids 1 - 3, asperulosidic acid, Daphylloside, and asperuloside, were isolated from the methanol extract of the leaves of Morinda tomentosa.
METHODS AND RESULTS:
Their chemical structures were elucidated by 1D- and 2D-NMR spectra and in comparison with those reported in the literature. The effects of these compounds on the endoplasmic reticulum stress in XBP1-eGFP-transfected the 293 T cells were measured. Compound 3 significantly reduced the ER-stress both in DMSO-treated and thapsigargin-treated cells. Unlike this compound, compound 3 selectively reduced thapsigargin-induced ER-stress without any effect on the level of XBP1 splicing in DMSO-treated cells.
CONCLUSIONS:
These results suggested that compounds 2 and 3 can be suggested as new ER stress regulators.
Daphylloside Description
Source: The leaves of Daphniphyllum macropodum
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Euphorbia factor L22

Catalog No: CFN95338
CAS No: 1613700-09-6
Price: $413/5mg
3'-Hydroxy-2,4,5-trimethoxydalberg...

Catalog No: CFN95410
CAS No: N/A
Price: $413/5mg
Pinocembroside

Catalog No: CFN95444
CAS No: 75829-43-5
Price: $118/20mg
Cistantubuloside C1

Catalog No: CFN95121
CAS No: 620632-36-2
Price: $298/10mg
Diosmin Impurity 5

Catalog No: CFN95311
CAS No: 122087-66-5
Price: $318/10mg
3,4-O-dimethylcedrusin

Catalog No: CFN95026
CAS No: 166021-14-3
Price: $388/10mg
Notoptol

Catalog No: CFN95218
CAS No: 88206-49-9
Price: $318/5mg
Fargesol

Catalog No: CFN95027
CAS No: 128855-64-1
Price: $318/20mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2401 mL 11.2007 mL 22.4014 mL 44.8029 mL 56.0036 mL
5 mM 0.448 mL 2.2401 mL 4.4803 mL 8.9606 mL 11.2007 mL
10 mM 0.224 mL 1.1201 mL 2.2401 mL 4.4803 mL 5.6004 mL
50 mM 0.0448 mL 0.224 mL 0.448 mL 0.8961 mL 1.1201 mL
100 mM 0.0224 mL 0.112 mL 0.224 mL 0.448 mL 0.56 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Nat Prod Commun. 2013 Nov;8(11):1507-8.
Three new iridoid glucoside salts from Hedyotis tenelliflora Growing in Vietnam.[Pubmed: 24427927]
Three new sodium salts of iridoid acids, deacetylasperulosidic acid sodium salt (1), teneoside D (2), and teneoside E (3) were isolated from the leaves of Hedyotis tenelliflora Blume (Rubiaceae), together with seven known iridoids, 6alpha-hydroxygeniposide (4), 6beta-hydroxygeniposide (5), 6-O-methyldeacetylasperulosidic acid methyl ester (6), 6-O-methylscandoside methyl ester (7), 6alpha-methoxygeniposidic acid (8), Daphylloside (9), and mollugoside methyl ester (10). Their chemical structures were elucidated by 1D and 2D NMR spectroscopy, as well as HR-ESI-MS analysis.
Momordicoside K

Catalog No: CFN92305
CAS No: 81348-84-7
Price: $ / mg
Oxymatrine

Catalog No: CFN99805
CAS No: 16837-52-8
Price: $40/20mg
Kirenol

Catalog No: CFN98867
CAS No: 52659-56-0
Price: $50/20mg
Biatractylolide

Catalog No: CFN95205
CAS No: 182426-37-5
Price: $268/10mg
11-Oxomogroside III

Catalog No: CFN92192
CAS No: 952481-53-7
Price: $318/10mg
Intermedine

Catalog No: CFN00285
CAS No: 10285-06-0
Price: $ /
Icariin

Catalog No: CFN99554
CAS No: 489-32-7
Price: $30/20mg
6-Methoxyluteolin

Catalog No: CFN92706
CAS No: 520-11-6
Price: $268/20mg
Alpha-pinene

Catalog No: CFN93285
CAS No: 80-56-8
Price: $30/20mg
6''-O-Malonylgenistin

Catalog No: CFN90631
CAS No: 51011-05-3
Price: $348/5mg
Tags: buy Daphylloside | Daphylloside supplier | purchase Daphylloside | Daphylloside cost | Daphylloside manufacturer | order Daphylloside | Daphylloside distributor