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Icariside I
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Icariside I
Price: $138 / 20mg
CAS No.: 56725-99-6
Catalog No.: CFN92550
Molecular Formula: C27H30O11
Molecular Weight: 530.5 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Epimedium brevicornu.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $46.8 / In-stock
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Icariside I is a metabolite product of Icariin.
Icariside I Description
Source: The herbs of Epimedium brevicornu.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.885 mL 9.4251 mL 18.8501 mL 37.7003 mL 47.1254 mL
5 mM 0.377 mL 1.885 mL 3.77 mL 7.5401 mL 9.4251 mL
10 mM 0.1885 mL 0.9425 mL 1.885 mL 3.77 mL 4.7125 mL
50 mM 0.0377 mL 0.1885 mL 0.377 mL 0.754 mL 0.9425 mL
100 mM 0.0189 mL 0.0943 mL 0.1885 mL 0.377 mL 0.4713 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Cell Physiol. 2013 Mar;228(3):513-21.
Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling.[Pubmed: 22777826]

METHODS AND RESULTS:
Icariin, a prenylated flavonol glycoside isolated from Epimedium herb, stimulates osteogenic differentiation of BMSCs and inhibits bone resorption activity of osteoclasts. Icariin, whose metabolites include Icariside I, Icariside II, icaritin, and desmethylicaritin, has no estrogenic activity. However, icariin is more potent than genistein in promoting osteogenic differentiation and maturation of osteoblasts. The existence of a prenyl group on C-8 of icariin molecular structure has been suggested to be the reason why icariin is more potent than genistein in osteogenic activity.
CONCLUSIONS:
Thus, the prenylflavonoids may represent a class of flavonoids with a higher osteogenic activity.
Ginkgolic acid C15:1

Catalog No: CFN90161
CAS No: 22910-60-7
Price: $118/20mg
Caftaric acid

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CAS No: 67879-58-7
Price: $138/20mg
Luteolin-7-O-glucoside

Catalog No: CFN98565
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Price: $60/20mg
Isosaponarin

Catalog No: CFN90133
CAS No: 19416-87-6
Price: $318/5mg
Rosmarinyl glucoside

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Price: $413/5mg
Myricitrin

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Eupatilin

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Price: $68/20mg
Cyanidin-3-O-sambubioside chloride

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Price: $643/10mg
Flavone

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Alisol A 24-acetate

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CAS No: 18674-16-3
Price: $118/20mg
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