Science | Nature | Cell | View More
Natural Products
Wilforlide A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Wilforlide A
Price: $80 / 20mg
CAS No.: 84104-71-2
Catalog No.: CFN97335
Molecular Formula: C30H46O3
Molecular Weight: 454.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Tripterygium wilfordii Hook.f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $25.4 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Sanford Burnham Prebys Medical ... (USA)
  • S.N.D.T. Women's University (India)
  • Seoul National University of Sc... (Korea)
  • Funda??o Universitária de Dese... (Brazil)
  • Melbourne University (Australia)
  • Michigan State University (USA)
  • National Research Council of Ca... (Canada)
  • University of Vienna (Austria)
  • Sri Ramachandra University (India)
  • Worcester Polytechnic Institute (USA)
  • Universidade Federal de Santa C... (Brazil)
  • More...
Package
Featured Products
Ganoderic acid G

Catalog No: CFN90801
CAS No: 98665-22-6
Price: $318/20mg
Strictosamide

Catalog No: CFN98237
CAS No: 23141-25-5
Price: $158/10mg
Hotrienol

Catalog No: CFN99583
CAS No: 20053-88-7
Price: $ / mg
Oroxin A

Catalog No: CFN99712
CAS No: 57396-78-8
Price: $128/20mg
20-O-Glucoginsenoside Rf

Catalog No: CFN95036
CAS No: 68406-27-9
Price: $318/5mg
Magnolol

Catalog No: CFN98872
CAS No: 528-43-8
Price: $30/20mg
Beta-boswellic acid

Catalog No: CFN90221
CAS No: 631-69-6
Price: $218/20mg
Isocorynoxeine

Catalog No: CFN98155
CAS No: 51014-29-0
Price: $128/20mg
Oxypaeoniflorin

Catalog No: CFN99589
CAS No: 39011-91-1
Price: $138/20mg
Forskolin

Catalog No: CFN90186
CAS No: 66575-29-9
Price: $40/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Wilforlide A is a quality control standard of Tripterygium Glycosides that be listed in Drug Standard of Ministry of Public Health of the People's Republic of China. Wilforlide A has obvious anti-inflammatory effects.
Targets: Immunology & Inflammation related
In vitro:
Fitoterapia. 2010 Dec;81(8):1109-12.
Comparative study on the anti-inflammatory and immune suppressive effect of Wilforlide A.[Pubmed: 20621167]
Tripterygium Glycosides (TG) is effective in the treatment of patients with a variety of inflammatory and autoimmune diseases, especially rheumatoid arthritis (RA) in clinical. Wilforlide A (T(1)) serves as a quality control standard of TG that be listed in Drug Standard of Ministry of Public Health of the People's Republic of China. The pharmacologic actions of T(1) remain to be unidentified.
METHODS AND RESULTS:
In this paper, we studied the anti-inflammatory and immune suppressive effect of T(1), and compared it with Triptolide (TP), which believed to be the major active component of TG. Carrageenan-induced rat pedal swelling, tampon-induced rat granulation, and mice ear inhibition rate of swelling trail results show that high-dose T(1) has obvious anti-inflammatory effect. Colorimetric detection contents of hemolysin, carbon elimination from plasma of mice, mice delayed hypersensitivity immune, and organ index were measured.
CONCLUSIONS:
The results show that T(1) has no significant immune suppressive activity, and there has a significant difference with TP and TG. Therefore, we think the content of TP also should be controlled as a supplement standard in order to ensure safe and effective medication.
Wilforlide A Description
Source: The herbs of Tripterygium wilfordii Hook.f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
2'-Rhamnoechinacoside

Catalog No: CFN95035
CAS No: 1422390-59-7
Price: $368/10mg
Pieceid-2''-O-gallate

Catalog No: CFN95226
CAS No: 105304-51-6
Price: $318/10mg
7-(4-hydroxy-3-methoxyphenyl)-1-ph...

Catalog No: CFN95139
CAS No: 79559-60-7
Price: $268/20mg
Schisphenin E

Catalog No: CFN95223
CAS No: 1311376-52-9
Price: $318/5mg
3',5-Dihydroxy-4',6,7-trimethoxyfl...

Catalog No: CFN95316
CAS No: 90850-99-0
Price: $318/5mg
2,11,12-Trihydroxy-7,20-epoxy-8,11...

Catalog No: CFN95428
CAS No: 1608462-12-9
Price: $318/10mg
Dichotomine B

Catalog No: CFN95193
CAS No: 755036-41-0
Price: $318/5mg
7-(4-Hydroxyphenyl)-1-phenyl-4-hep...

Catalog No: CFN95140
CAS No: 100667-52-5
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1993 mL 10.9963 mL 21.9925 mL 43.985 mL 54.9813 mL
5 mM 0.4399 mL 2.1993 mL 4.3985 mL 8.797 mL 10.9963 mL
10 mM 0.2199 mL 1.0996 mL 2.1993 mL 4.3985 mL 5.4981 mL
50 mM 0.044 mL 0.2199 mL 0.4399 mL 0.8797 mL 1.0996 mL
100 mM 0.022 mL 0.11 mL 0.2199 mL 0.4399 mL 0.5498 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Ganoderic acid G

Catalog No: CFN90801
CAS No: 98665-22-6
Price: $318/20mg
Strictosamide

Catalog No: CFN98237
CAS No: 23141-25-5
Price: $158/10mg
Hotrienol

Catalog No: CFN99583
CAS No: 20053-88-7
Price: $ / mg
Oroxin A

Catalog No: CFN99712
CAS No: 57396-78-8
Price: $128/20mg
20-O-Glucoginsenoside Rf

Catalog No: CFN95036
CAS No: 68406-27-9
Price: $318/5mg
Magnolol

Catalog No: CFN98872
CAS No: 528-43-8
Price: $30/20mg
Beta-boswellic acid

Catalog No: CFN90221
CAS No: 631-69-6
Price: $218/20mg
Isocorynoxeine

Catalog No: CFN98155
CAS No: 51014-29-0
Price: $128/20mg
Oxypaeoniflorin

Catalog No: CFN99589
CAS No: 39011-91-1
Price: $138/20mg
Forskolin

Catalog No: CFN90186
CAS No: 66575-29-9
Price: $40/20mg
Tags: buy Wilforlide A | Wilforlide A supplier | purchase Wilforlide A | Wilforlide A cost | Wilforlide A manufacturer | order Wilforlide A | Wilforlide A distributor