Isoastilbin has anti-acne and tyrosinase inhibition properties.Isoastilbin, neoastilbin, astilbin and taxifolin have antimicrobial activities, they depress the growth of Streptococcus sobrinus (S. sobrinus) over a concentration range of 9.32-42.7 ug/ml and show GTase inhibitory activity with IC50 values in the range 27.4-57.3 ug/ml.
Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively. Lauric acid displays preferential antineoplastic property, including induction of apoptosis in a CRC cell line.
1. Terchebulin, flavogallonic acid and punicalagin have antiplasmodial activity, the IC50s of them range between 8-21 microg/ml (8-40 microM) against Plasmodium falciparum 3D7 and K1.
2. Terchebulin shows good antibacterial activity against Propionibacterium acnes, minimum inhibitory concentration (MIC) = 125 ug/ml and minimum bactericidal concentration (MBC) = 250 ug/ml, demonstrates that terchebulin has potentiality as an anti-acne agent.