1. 10-Hydroxycamptothecin is an indole alkaloid isolated from a Chinese tree, Camptotheca acuminata, and has a wide spectrum of anticancer activity in vitro and in vivo mainly through inhibitory effects on topoisomerase I.
2. 10-Hydroxycamptothecine can prevent fibroblast proliferation and epidural scar adhesion after laminectomy in rats.
3. 10-Hydroxycamptothecin has antiangiogenic potential.