Science | Nature | Cell | View More
Bioactive Products
Anti-inflammatory Compound Library
A unique collection of 552 Anti-inflammatory natural compound library for Anti-inflammatory screening and New Anti-inflammatory drug research
Catalog No: B72a26 Anti-inflammatory Compound Library
Screening Details
Size: 1mg/well * 552 Compounds
2mg/well * 552 Compounds
Cat. No. Information
CFN99399 Protopine

Protopine acts as a potent inhibitor of thromboxane synthesis and PAF with hepatoprotective, antidepressant, antioxidant, antispasmodic and relaxant properties. Protopine is also a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines. Protopine blocks phosphorylation of mitogen-activated protein kinases (MAP kinases) and also blocks activation of a nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB).
CFN99103 Rosmarinic acid

Rosmarinic acid has antiviral, antibacterial, antiinflammatory, neuroprotective, anticancer, anti-lipid peroxidative, apoptotic,and antioxidant activities. It is used for food preservation, and to treat peptic ulcers, arthritis, cataract, cancer, rheumatoid arthritis, bronchial asthma, and several human neurodegenerative diseases caused by oxidative stress. Rosmarinic acid has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling. It inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.
CFN99107 Isoimperatorin

Isoimperatorin has analgesic, hepatoprotective, antimicrobial, anti-inflammatory, vascular relaxing and anticancer activities. It inhibited the expression of COX, TNF-α, PPAR-γ,ERK1/2, PI3K, and PKC. It showed significant inhibitory effects on acetylcholinesterase (AChE) with the IC50 of 74.6 uM, it also showed different inhibitory effects on all of the six CYP isoenzymes(human CYP1A2, 2B6, 2C9, 2C19, 2D6 and 3A4 enzymes).
CFN99402 Pimpinellin

Pimpinellin has phototoxic, it acts as antagonist of proteins with GABA receptor activity. Pimpinellin has anti- inflammatory, and cytotoxic activities. Pimpinellin also has anti-bacterial activity, it shows inhibitory activity against Mycobacterium tuberculosis strain H37Ra , with MICs of 812 uM and IC50s of 389 uM.
CFN99111 Baicalin

Baicalin has antioxidant, anti-inflammatory, anti-apoptotic, and neuroprotection actions, it is a known prolyl endopeptidase inhibitor, affects the GABA receptors, and reduces the expression of NF-κB. Baicalin may have significant therapeutic benefits against diabetic complications and atherosclerosis.