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Bioactive Products
Anti-photoaging Compound Library
A unique collection of 36 Anti-photoaging natural compounds
Catalog No: C1 Anti-photoaging Compound Library
Screening Details
Size: 1mg/well * 36 Compounds
2mg/well * 36 Compounds
Cat. No. Information
CFN97844 Sulfuretin

Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways. Sulfuretin may have a potential role for neuroprotection, possibly through inhibition of phosphorylation of MAPK, PI3K/Akt, and GSK-3β, which leads to mitochondrial protection, NF-κB modulations and subsequent suppression of apoptosis via ROS-dependent pathwaysand, may be used as a therapeutic agent for PD; it also may have therapeutic value in preventing or delaying the progression of rheumatoid arthritis.Sulfuretin has therapeutical effect on leukemia, due to its potent apoptotic activity through the extrinsic pathway driven by a Fas-mediated caspase-8-dependent pathway.
CFN92132 Pelargonidin chloride

Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway. It also has the antianaphylactic properties, which might be related to the increase of both cyclic AMP and cyclic GMP through the inhibition of phosphodiesterase. Pelargonidin chloride has strong antioxidative activity in a liposomal system and reduced the formation of malondialdehyde by UVB irradiation.
CFN92135 Cyanidin-3-O-rutinoside chloride

Cyanidin-3-O-rutinoside chloride has antioxidant activity. It has LPO inhibition at a 0.25 μM concentration, inhibits the COX-1 enzyme by 45.2 and COX-2 by 61.5 at 5 μM. Cyanidin-3-O-rutinoside chloride improves vision in humans (for night blindness).
CFN90512 10-Hydroxy-2-decenoic acid

10-Hydroxy-2-decenoic acid is a potential HDACI which inhibits the proliferation of FLS cells by PI3K-AKT pathway; it exerts an inhibitory effect on VEGF-induced angiogenesis, partly by inhibiting both cell proliferation and migration. 10-Hydroxy-2-decenoic acid activates AMPK, and insulin independently enhances glucose uptake following translocation of Glut4 to PM; it also can prevent UVA-induced damage and inhibit MMP-1 and MMP-3 expressions.
CFN90555 Pogostone

Pogostone possesses potent anti-bacterial and anti-fungal activities, it also exhibits an immunosuppressive property by directly blocking T cell proliferation as well as altering inflammatory cytokine profile. Pogostone could exert a gastro-protective effect against gastric ulceration, and the underlying mechanism might be associated with the stimulation of PGE2, improvement of antioxidant and anti-inflammatory status, as well as preservation of NP-SH.