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Bioactive Products
Antiangiogenic Compound Library
A unique collection of 69 Antiangiogenic natural compound library for Antiangiogenic screening
Catalog No: B94 Antiangiogenic Compound Library
Screening Details
Size: 1mg/well * 69 Compounds
2mg/well * 69 Compounds
Cat. No. Information
CFN90204 Erianin

Erianin, often used as an antipyretic and analgesic agent, it also has antiangiogenic action by inhibiting endothelial metabolism in a JNK/SAPK-dependent manner and inducing endothelial cytoskeletal disorganisation.
CFN90212 Gamabufotalin

Gamabufotalin has been used for treatment of COX-2-mediated diseases and cancer therapy, it triggers c-Myc degradation via induction of WWP2 in multiple myeloma(MM) cells. Gamabufotalin strongly inhibit cancer cell growth and inflammatory response, it inhibits angiogenesis by inhibiting the activation of VEGFR-2 signaling pathways and could be a potential candidate in angiogenesis-related disease therapy.
CFN90219 1-O-Acetyl britannilactone

1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling. 1-O-Acetyl britannilactone may be one anti-inflammatory drug which inhibits the expression of COX-2 gene by blocking NF-κB activation and thus suppresses the inflammatory response to LPS in vascular smooth muscle cells.
CFN97594 Isolicoflavonol

Isolicoflavonol is a potential cancer chemopreventive agent.
CFN90239 Indirubin

Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM. Indirubin has anticancer, anti-inflammatory,antiviral,anti-allergic contact dermatitis effects. Each indirubin derivative acts on the DNA binding of NF-Y and represses the MDR1 gene promoter with tumor cell-type specificity.Indirubin derivatives have a potential to be used as an adjunct to antiviral therapy for the treatment of severe human H5N1 disease.