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Bioactive Products
Antihypertensive Compound Library
A unique collection of 51 Antihypertensive natural compound library for Antihypertensive screening
Catalog No: Bb138 Antihypertensive Compound Library
Screening Details
Size: 1mg/well * 51 Compounds
2mg/well * 51 Compounds
Cat. No. Information
CFN99994 Pinoresinol diglucoside

Pinoresinol diglucoside is a putative α-glucosidase inhibiting compound, has antihypertensive activity. It is a heat shock factor 1 inducer, increased expression of HSF1 by a factor of 1.041 at 3 μM.
CFN98112 Reserpine

Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug. Reserpine ameliorates Abeta toxicity in the Alzheimer's disease model in Caenorhabditis elegans, it can significantly delay paralysis and increase the longevity in this model.
CFN98237 Strictosamide

Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain. Strictosamide is slightly toxic to Charles River mouse (LD(50)=723.17 mg/kg), producing CNS depression and kidney toxicity. Strictosamide has nonsignificant in vitro and in vivo effect on kidney Na(+),K(+)-ATPase activity but produced an in vivo increase of Na(+),K(+)-ATPase activity of brain.
CFN98131 Rhynchophylline

Rhynchophylline, a noncompetitive antagonist of the NMDA receptor, which has anti-inflammatory, anti-hypertension, cardiacprotective and neuroprotective activities. Rhynchophylline can markedly inhibit rabbit platelet aggregation induced by ADP or thrombin possibly by depressing the inflow of Ca2+ and the rise of the cytoplasmic free calcium level in platelet.Rhynchophylline can reduce the systolic blood pressure (SBP) of spontaneously hypertensive rats (SHR) significantly, decrease plasma Ang II, ADMA, and AT1R levels, and promote serum NO and NOS levels, which has the protection of vascular endothelial function.
CFN98144 Peimisine

Peimisine may have antihypertensive action, it can inhibit angiotensin I converting enzyme activity in a dose-dependent manner(the IC50 value of 526.5 microM). Peimisine can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. It plays a protective role against LPS-induced acute lung injury, and against the experimental hepatic fibrosis formation.