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Bioactive Products
Antileukaemic Compound Library
A unique collection of 35 Antileukaemic natural compound library for Antileukaemic screening
Catalog No: B29 Antileukaemic Compound Library
Screening Details
Size: 1mg/well * 35 Compounds
2mg/well * 35 Compounds
Cat. No. Information
CFN92259 Ponicidin

Ponicidin has anti-leukemia, immunoregulatory and anti-inflammatory functions, it also has anti-viral function especially in the upper respiratory tract infection. Ponicidin has anti-cancer activity against gastric carcinoma and lung cancer; can inhibit growth and induce apoptosis of gastric carcinoma cell line MKN28, via the signaling pathway regulated by Janus kinase 2 (JAK2) and signal transducers and activators of transcription 3 (STAT3).
CFN92299 8-Shogaol

8-Shogaol can induce apoptosis in a time- and concentration-dependent manner by reactive oxygen species production and depletion of glutathione in HL-60 cells.
CFN90537 Embelin

Embelin is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.Embelin has antitumor, antioxidant and anti-inflammatory activities. Embelin can enhance TRAIL-induced cell apoptosis through DR4 and DR5 upregulation and decrease IL-6-induced STAT3 phosphorylation, that combination of low-toxicity Embelin and TRAIL may become as a potential antileukemia strategy.
CFN92616 Zederone

Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of biological reactive metabolites and that cause the oxidative stress and liver cell injuries.
CFN92722 Schisanlignone A

Schisanlignone A and Schisanlignone B show a significant activity against Leukaemia P-388 cell (IG(50) =10 and 40ug/mL, respectively) in vitro.