Bioactive Products
| A unique collection of 32 Antimalaric natural compounds for antimalaric drug research | ||
| Catalog No: | B81 | Antimalaric Compound Library Screening Details |
| Size: | 1mg/well * 32 Compounds 2mg/well * 32 Compounds | |
| Cat. No. | Information |
| CFN92109 | Digitolutein Digitolutein has inhibition on the growth of Plasmodium falciparum in vitro. |
| CFN92129 | Eurycomalactone Eurycomalactone as a potent NF-κB inhibitor with the IC50 value of less than 1 uM. It shows antiplasmodial activity against Gombak A isolate. Eurycomalactone displays potent activity against all the tested cell lines [colon 26-L5 carcinoma (IC50 = 0.70 microM), B16-BL6 melanoma (IC50 = 0.59 microM), Lewis lung carcinoma (IC50 = 0.78 microM), and a human lung A549 adenocarcinoma (IC50 = 0.73 microM)]. |
| CFN92148 | Methyltanshinonate Methyltanshinonate shows antiplasmodial and antitrypanosomal activities. It may have antioxidative activity. |
| CFN92150 | Isochamaejasmine Isochamaejasmine has inhibition of NF-kappaB activation, which could reverse the anti-apoptotic effect; it induces apoptosis in leukemia cells by inhibiting the activity of Bcl-2 family proteins, providing evidence for further studying the underlying anti-cancer mechanism of S. chamaejasme L. Isochamaejasmine shows antiplasmodial activity, with an IC(50) of 7.3+/-3.8 microM, but the selectivity was rather limited. |
| CFN92178 | Ferruginol Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells. Ferruginol has antimicrobial and antifungal activities against wood-rot fungi (basidiomycetes), can cause cellular dysfunction and damage, lead to growth inhibition and autophagic cell death of fungi. |
