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  • Bioactive Products
    Catalog No. Information
    CFN99444 Cannabidiol

    1. Cannabidiol can reduce the anxiety provoked by Delta-9-tetrahydrocannabinol (delta-9-THC) in normal volunteers, and the effects of cannabidiol , as opposed to those of delta 9-THC, may be involved in the antagonism of effects between the two cannabinoids.
    2. Cannabidiol has a potent anti-arthritic effect in collagen-induced arthritis through its combined immunosuppressive and anti-inflammatory actions.
    3. Cannabidiol has a pharmacological profile similar to that of atypical antipsychotic drugs.
    4. Cannabidiol is a potent inhibitor of cancer cell growth (IC50 between 6.0 and 10.6 microM), with significantly lower potency in noncancer cells.
    5. Cannabidiol exerts a combination of neuroprotective, anti-oxidative and anti-apoptotic effects against beta-amyloid peptide toxicity, and that inhibition of caspase 3 appearance from its inactive precursor, pro-caspase 3, by cannabidiol is involved in the signalling pathway for this neuroprotection.
    6. Cannabidiol may have great therapeutic potential in the treatment of diabetic complications, and perhaps other cardiovascular disorders, by attenuating oxidative/ nitrative stress, inflammation, cell death and fibrosis.
    CFN99599 Sinensetin

    1. Sinensetin is a polymethoxylated flavonoids in citrus fruit, as a novel antiangiogenesis agent, has potential for anti-carcinogenesis, antitumor, and cardiovascular protective activity.
    2. Sinensetin has antioxidative effect and has anti-inflammatory by regulating the protein level of inhibitorκB-α, which may be utilized in the development of novel anti-inflammatory treatments.
    3. Sinensetin enhances activation of protein kinase A and increases intracellular cAMP levels in 3T3-L1 preadipocytes, it stimulates lipolysis via a cAMP pathway in mature 3T3-L1 adipocytes, suggests that sinensetin enhances adipogenesis and lipolysis by increasing cAMP levels in adipocytes.
    CFN99910 Ligustrazine Hydrochloride

    1. Ligustrazine Hydrochloride has certain protection effect on the vascular endothelium undergoing cardiopulmonary bypass (CPB), and lower excessive activation of coagulation reaction and inflammation reaction in patients undergoing CPB.
    2. Ligustrazine hydrochloride can inhibit the activation of humai platelet following severe brain injury , improve t'ie balance, of TXA2 - PGI2 within the circulatory blood, suggests that it may be used as one of the agents to treat brain injury.
    3. Ligustrazine Hydrochloride can exert down-regulate effects on Colon26 secretion of immunosuppressors and its tumor immunosuppression, one of the mechanisms is reducing tumor immunosuppression of Colon26 through decreasing its secretion of immunosuppressors.
    4. Ligustrazine hydrochloride injection has antithrombotic effect on the model of induced arteriovenous shunt thrombosis.
    5. Ligustrazine Hydrochloride has a protective effect on homocysteine-injured ECV304 cells.
    CFN98034 Parthenolide

    1. Parthenolide is an E3 Ligase Inhibitor.
    2. Parthenolide specifically depletes histone deacetylase 1 protein and induces cell death through ataxia telangiectasia mutated.
    3. Parthenolide has antiproliferative activity of parthenolide against three human cancer cell lines and human umbilical vein endothelial cells.
    4. Parthenolide is an anti-inflammatory agent, can inhibit IκB Kinase, NF-κB Activation, and Inflammatory Response in Cystic Fibrosis Cells and Mice.
    CFN98156 Ophiopogonin D

    1. Ophiopogonin D can prevent tumor metastasis, inhibit the proliferation of MDA-MB-435 melanoma cells.
    2. Ophiopogonin D protects cardiomyocytes against DOX-induced injury, at least in part, through reducing ROS accumulation and alleviating ERS.
    3. Ophiopogonin D has anti-inflammatory and anti-oxidant properties, could act as expectorants in diverse inflammatory pulmonary diseases by increasing mucin production and secretion on airway epithelial cells .