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Bioactive Products
Cytotoxic Compound Library
A unique collection of 129 Cytotoxic natural compounds used for Cytotoxic research
Catalog No: B913 Cytotoxic Compound Library
Screening Details
Size: 1mg/well * 129 Compounds
2mg/well * 129 Compounds
Cat. No. Information
CFN99368 Cedrelone

Cedrelone exhibits antifeedant activity, it has insecticidal activity, it inhibits arval growth of P. saucia, and the molting of the milkweed bug, Oncopeltus fasciatus. Cedrelone and its derivatives exert antimicrobial activities, bromohydroxy cedrelone and Michael adduct show good antifungal activity. Cedrelone is also a very potent inducer of apoptosis, it can cause cell cycle arrest, it shows significant cytotoxicity against cancer cell lines, such as -60, SMMC-7721, A-549, MCF-7 and SW480.
CFN99369 3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone

5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it shows considerably activity against HIV-1 reverse transcriptase. It exhibits cytotoxic activity against P-388 cell lines, it can inhibit DNA topoisomerase IIα activity, which may be responsible for the observed cytotoxicity.
CFN99387 Hyptadienic acid

Hyptadienic acid exhibits moderate cytotoxicity against HepG2 cells.It also shows a marked anti-inflammatory effect, it also exhibits strong antitumor-promoting activity in an in vivo two-stage carcinogenesis test of mouse tumor by using 7,12-dimethylbenz(a)anthracene (DMBA) as an initiator and TPA as a promoter.
CFN99391 2',4'-Dihydroxy-3',6'-dimethoxychalcone

2',4'-Dihydroxy-3',6'-dimethoxychalcone has cytotoxic, anti-inflammatory activity and anti-cholinesterase activities, it has significant NO inhibitory activity.
CFN99402 Pimpinellin

Pimpinellin has phototoxic, it acts as antagonist of proteins with GABA receptor activity. Pimpinellin has anti- inflammatory, and cytotoxic activities. Pimpinellin also has anti-bacterial activity, it shows inhibitory activity against Mycobacterium tuberculosis strain H37Ra , with MICs of 812 uM and IC50s of 389 uM.