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Bioactive Products
Cat. No. Information
CFN00433 Trichodesmine

Trichodesmine has greater lethality and neurotoxicity than monocrotaline, because of the two structural characteristics:(a) steric hindrance at position 14 of dehydroTrichodesmine results in greater resistance to hydrolysis, allowing more to be released from the liver and to be delivered to the brain;(b) the larger isopropyl substituent at position 14 of dehydroTrichodesmine renders the molecule more lipophilic, leading to greater penetration of the brain.
CFN90160 Methysticin

Methysticin is a potent NF-kappaB inhibitor in kava with minimum toxicity, it possesses hepatotoxic, anticonvulsant and neuroprotective properties, it contributes to CYP1A1 induction.
CFN97708 Precocene II

Precocene II , an insect growth regulator, it inhibits the production of juvenile hormone (JH) in insects, it is highly toxic to adult female Rhodnius and treatment of newly emerged females prevented oogenesis. Precocene II is structurally related to several naturally occurring carcinogenic and non-carcinogenic alkenylbenzenes, is genotoxic and produces hepatic centrolobular necrosis in rats.