1. Dehydrocorydaline has antitumor activity.
2. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.
3. Dehydrocorydaline reduces the viability of macrophage-derived RAW264.7 cells and primary macrophages in the presence of LPS.
4. Dehydrocorydaline inhibits the elevation of mitochondrial membrane potential and induces ATP depletion in LPS-stimulated macrophages but neither affects basal mitochondrial membrane potential nor ATP content in non-stimulated macrophages.