Bioactive Products
| A unique collection of 50 Pro-apoptotic natural compound library for Pro-apoptotic screening | ||
| Catalog No: | B93 | Pro-apoptotic Compound Library Screening Details |
| Size: | 1mg/well * 50 Compounds 2mg/well * 50 Compounds | |
| Cat. No. | Information |
| CFN97283 | Schinifoline Schinifoline has cytotoxic activity, it also shows in vitro radiosensitising, cell cycle and apoptotic-inducing effects. |
| CFN97339 | Rocaglamide Rocaglamides are potent natural anticancer products that inhibit proliferation of various cancer cells at nanomolar concentrations, it prevents tumor growth and sensitize resistant cancer cells to apoptosis by blocking the MEK-ERK-eIF4 pathway. Rocaglamides can suppress the PMA-induced expression of NF-kappaB target genes and sensitize leukemic T cells to apoptosis induced by TNFalpha, cisplatin, and gamma-irradiation, suggests that rocaglamide derivatives could serve as lead structures in the development of anti-inflammatory and tumoricidal drugs. Rocaglamide and a XIAP inhibitor cooperatively sensitize TRAIL-mediated apoptosis in Hodgkin's lymphomas. |
| CFN90158 | Alisol B acetate Alisol B acetate can induce Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells, the Bax activation and translocation from the cytosol to nucleus might be a crucial response to the apoptotic effect. Alisol B acetate exhibits an antiproliferative effect in SGC7901 cells by inducing apoptosis, apoptosis of SGC7901 cells involves mitochondria-caspase and PI3K/Akt dependent pathways. |
| CFN97482 | Tenacigenoside A Tenacigenoside A and 11α-O-benzoyl-12β-O-acetyltenacigenin B (TGTB) can significantly increase tumor cell apoptosis on lymphoma bearing mice primarily through down-regulation of BCL2 and BCL-XL, and up-regulation of BID. |
| CFN90170 | Theaflavin-3-gallate Theaflavin-3-gallate has anticancer and apoptotic effects in non-small cell lung carcinoma, it acts as prooxidants and induce oxidative stress, with carcinoma cells more sensitive than normal fibroblasts. Theaflavin-3-gallate can play a role in decreased intestinal cholesterol absorption via inhibition of micelle formation. |
