Science | Nature | Cell | View More
Bioactive Products
Toxicity Compound Library
A unique collection of 60 Toxicity natural compounds for screening
Catalog No: Bb201 Toxicity Compound Library
Screening Details
Size: 1mg/well * 60 Compounds
2mg/well * 60 Compounds
Cat. No. Information
CFN92867 3-O-(2'E,4'Z-Decadienoyl)ingenol

Kansuiphorin C and 3-O-(2′E,4′Z-decadienoyl)-ingenol exhibit significant anticomplement activity with respective 50% inhibitory concentration values of 44.1±3.8 and 89.5±5.5 uM. 20-O-acetyl-[3-O-(2'E,4'Z)-decadienoyl]-ingenol and 3-O-(2'E,4'Z)-decadienoylingenol show the same antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 microg/cotton ball.
CFN92868 3-O-(2'E,4'E-Decadienoyl)ingenol

3-O-(2'E,4'E-Decadienoyl)ingenol , one toxic terpenoid from raw Gansui.3-O-(2′E,4′E-decadienoyl)-ingenol and 3-O-(2′E,4′Z-decadienoyl)-20-O-acetyl-ingenol show cytotoxicity on Namalwa cells with IC 50 values of 7.6 and 5.2 umol·L-1, respectively.
CFN97986 Enniatin B1

Enniatin B1 has antifungal effects. It induces apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. Enniatin B1 also has intestinal toxicity.
CFN90610 7Beta-Hydroxycholesterol

7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells. 7beta-Hydroxycholesterol and 7-ketocholesterol have dual cytotoxic effects on the cells of the vascular wall by their ability to induce apoptosis in endothelial and smooth muscle cells and necrosis in fibroblasts. 7beta-Hydroxycholesterol can inhibit the proliferation of NCI-H460 cells through apoptosis via caspase activation. It can reinforce the susceptibility of K562 adriamycin-resistant cells to this drug, it also can enhance radiosensitivity in RDM4 cells.
CFN90660 3-Deoxyaconitine

3-Deoxyaconitine has toxicity.