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Natural Products
Huperzia serrata (Thunb.) Trev.
Huperzia serrata (TCM = Qian Ceng Ta/Jin Bu Huan) is a plant known as a firmoss which contains the acetylcholinesterase inhibitor huperzine A. It is widely distributed over-the-counter as a nootropic and dietary supplement. It may also be used to treat Alzheimer's disease.This species is native to India and southeast Asia.
A new Lycopodium alkaloid, huperserratinine, was isolated from Huperziaserrata and its structure and NMR data were assigned unambiguously by a combination of NMR experiments and computer modelling calculations. The pH-zone refining centrifugal partition chromatography technique was used to separate the two acetylcholinesterase inhibitors huperzines A and B from a crude alkaloid extract of the club moss Huperziaserrata. Huperzine P (1), a new irregular fawcettimine-type Lycopodium alkaloid, was isolated from Huperziaserrata and the absolute stereostructure was established by 2D NMR and X-ray crystallographic analysis.
Huperzia serrata (Thunb.) Trev.
Research products of Huperzia serrata (Thunb.) Trev.
Catalog Product Name CAS Number Manual
CFN99959Huperzine A120786-18-7  PDF
CFN99960Huperzine B103548-82-9  PDF
CFN9949521-Episerratenediol1449-06-5  PDF
CFN98216Serratenediol2239-24-9  PDF
CFN98339Serratenediol diacetate27832-84-4  PDF
CFN99958(-)-Huperzine A102518-79-6  PDF
CFN99916Beta-Sitosterol83-46-5  PDF
CFN98913Lupeol545-47-1  PDF
CFN98848Physcion521-61-9  PDF
CFN98843Apigenin520-36-5  PDF
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