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Natural Products
Rauvolfia yunnanensis Tsiang

Rauvolfia yunnanensis Tsiang, belonging to the Apocynaceae,is indigenous to southwestern China, and its roots are utilized locally for the remedy of scab. Recently, several structurally interesting indole alkaloids were isolated from this plant.6–8 As one part of our research program exploring bioactive monoterpene indole alkaloids from Chinese species of Rauvolfia, phytochemical analysis from the methanol extract of aerial parts of R. yunnanensis led to the isolation of three new alkaloids, rauvoyunines A–C. This paper reports the isolation and structure elucidation of new compounds and cytotoxic evaluation of selected compounds.
Three new indole alkaloids, 10-methoxy-16-de(methoxycarbonyl)pagicerine (1), (5β)-17-O-deacetyl-5,11-dimethoxyakuammiline (2), and ((16S,19E)-N1-(hydroxymethyl)isositsirikine (3) were isolated from the roots of Rauvolfia yunnanensis, together with seven known alkaloids. The structures of the new compounds were elucidated by in-depth spectroscopic and mass-spectrometric analyses.

Rauvolfia yunnanensis Tsiang
Research products of Rauvolfia yunnanensis Tsiang
Catalog Product Name CAS Number Manual
CFN98112Reserpine50-55-5  PDF
CFN97109Tetrahydroalstonine6474-90-4  n/a
CFN98760Aricine482-91-7  n/a
CFN99819Isocarapanaubine17391-09-2  PDF
CFN90147Yohimbine146-48-5  PDF
CFN98761Ajmalicine483-04-5  n/a
CFN98375Robinin301-19-9  PDF
CFN98542Syrosingopine84-36-6  PDF
CFN97028Tombozine604-99-9  n/a
CFN97966Rauvoyunine C1211543-01-9  n/a
CFN99867Serpentine18786-24-8  PDF
CFN96687Rauvoyunine B1414883-82-1  n/a
CFN96696Rauvoyunine A1414883-81-0  n/a
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