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1,2,3,6,7-Pentamethoxyxanthone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1,2,3,6,7-Pentamethoxyxanthone
Price:
CAS No.: 64756-86-1
Catalog No.: CFN89241
Molecular Formula: C18H18O7
Molecular Weight: 346.33 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Powder
Source: The roots of Polygala tenuifolia.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Biological Activity
Description: 1,2,3,6,7-Pentamethoxyxanthone is a natural product from Polygala tenuifolia.
1,2,3,6,7-Pentamethoxyxanthone Description
Source: The roots of Polygala tenuifolia.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8874 mL 14.4371 mL 28.8742 mL 57.7484 mL 72.1855 mL
5 mM 0.5775 mL 2.8874 mL 5.7748 mL 11.5497 mL 14.4371 mL
10 mM 0.2887 mL 1.4437 mL 2.8874 mL 5.7748 mL 7.2185 mL
50 mM 0.0577 mL 0.2887 mL 0.5775 mL 1.155 mL 1.4437 mL
100 mM 0.0289 mL 0.1444 mL 0.2887 mL 0.5775 mL 0.7219 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhong Yao Cai. 2014 Sep;37(9):1594-6.
Chemical constituents of Polygala tenuifolia root.[Pubmed: 25857159]
To study the chemical constituents from the root of Polygala tenuifolia.
METHODS AND RESULTS:
Silica gel,Sephadex LH-20 and ODS chromatographic techniques were used to study the chemical constituents of Polygala tenuifolia, and the chemical structures were elucidated by application of spectral data. Eight-compounds were obtained and their structure were identified as 7-hydroxy-1-methoxy-2,3-methylenedioxyxanthone(1), 1, 7-dihydroxy-2, 3-dimethoxyxanth one(2), 1,3,6-trihydroxy-2, 7-dimethoxyxanthone(3),7-hydroxy-1,2, 3-trimethoxyxanthone(4), 1,2,3,6,7-Pentamethoxyxanthone(5), 1,3, 7-trihydroxy-2, 6-dimethanoxyxanthone (6),7-hydroxy-1-methoxyxanthone(7) and 1,7-dihydroxy-3,4-dimethoxyxanthone(8).
CONCLUSIONS:
Compounds 1,6,7 and 8 are isolated from Polygala tenuifolia for the first time.
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