1,3,7-Trihydroxy-2-prenylxanthone | CAS:20245-39-0

1,3,7-Trihydroxy-2-prenylxanthone

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Product Name	1,3,7-Trihydroxy-2-prenylxanthone
Price:
CAS No.:	20245-39-0
Catalog No.:	CFN98022
Molecular Formula:	C₁₈H₁₆O₅
Molecular Weight:	312.3 g/mol
Purity:	>=98%
Type of Compound:	Xanthones
Physical Desc.:	Yellow powder
Source:	The fruits of Garcinia mangostana
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

1,3,7-Trihydroxy-2-prenylxanthone shows weak antibacterial activity against the bacterium.

Targets:

Antifection

In vitro:

Chem Biodivers. 2004 Sep;1(9):1385-90.

Antimicrobial activity of hydrophobic xanthones from Cudrania cochinchinensis against Bacillus subtilis and methicillin-resistant Staphylococcus aureus.[Pubmed: 17191916]

METHODS AND RESULTS:
Ten xanthones with one or two isoprenoid groups and a prenylated benzophenone isolated from roots of Cudrania cochinchinensis (Moraceae) were tested for their antimicrobial activities against Bacillus subtilis and methicillin-resistant Staphylococcus aureus (MRSA). Among these compounds, gerontoxanthone H exhibited considerable antibacterial activity against B. subtilis (MIC = 1.56 microg/ml). Four xanthones, gerontoxanthone I, toxyloxanthone C, cudraxanthone S, and 1,3,7-Trihydroxy-2-prenylxanthone, showed weak antibacterial activity against the bacterium (MICs = 3.13-6.25 microg/ml).
CONCLUSIONS:
These compounds also exhibited similar MIC values against methicillin-sensitive S. aureus, MRSAs, and Micrococcus luteus.

Phytomedicine. 2005 Jun;12(6-7):510-3.

Antimicrobial activity of isoprenoid-substituted xanthones from Cudrania cochinchinensis against vancomycin-resistant enterococci.[Pubmed: 16008130]

METHODS AND RESULTS:
Ten xanthones with one or two isoprenoid groups and a prenylated benzophenone isolated from roots of Cudrania cochinchinensis (Moraceae) were tested for their antimicrobial activities against vancomycin-resistant enterococci (VRE).
CONCLUSIONS:
Among these compounds, gerontoxanthone H exhibited considerable antibacterial activity against five VRE strains (VanA, VanB and VanC) (MICs = 1.56 microg/ml). Four xanthones, 1,3,7-Trihydroxy-2-prenylxanthone, gerontoxanthone I, alvaxanthone and isoalvaxanthone, showed weaker antibacterial activity against these VREs (MICs = 3.13-6.25 microg/ml).

1,3,7-Trihydroxy-2-prenylxanthone Description

Source:	The fruits of Garcinia mangostana
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antibacterial Compound Library Xanthones Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.202 mL	16.0102 mL	32.0205 mL	64.041 mL	80.0512 mL
5 mM	0.6404 mL	3.202 mL	6.4041 mL	12.8082 mL	16.0102 mL
10 mM	0.3202 mL	1.601 mL	3.202 mL	6.4041 mL	8.0051 mL
50 mM	0.064 mL	0.3202 mL	0.6404 mL	1.2808 mL	1.601 mL
100 mM	0.032 mL	0.1601 mL	0.3202 mL	0.6404 mL	0.8005 mL

CFN98022	1,3,7-Trihydroxy-2-prenylxanthone	20245-39-0	312.3	C₁₈H₁₆O₅
CFN97264	1,7-Dihydroxy-3-methoxy-2-prenylxanthone	77741-58-3	326.4	C₁₉H₁₈O₅
CFN99202	1,5,8-Trihydroxy-3-methoxy-2-prenylxanthone	110187-11-6	342.4	C₁₉H₁₈O₆
CFN99016	1,4,5,6-Tetrahydroxy-7-prenylxanthone	1001424-68-5	328.3	C₁₈H₁₆O₆
CFN99675	1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone	160623-47-2	342.4	C₁₉H₁₈O₆
CFN97493	O-Demethylforbexanthone	92609-77-3	326.3	C₁₈H₁₄O₆
CFN91900	Hyperxanthone E	819860-76-9	328.32	C₁₈H₁₆O₆
CFN99206	Garcinexanthone A	1107620-67-6	342.4	C₁₉H₁₈O₆
CFN89056	7-Prenyljacareubin	94513-60-7	394.42	C₂₃H₂₂O₆
CFN89137	Pyranojacareubin	78343-62-1	392.40	C₂₃H₂₀O₆