ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
More articles cited ChemFaces products.
J Pharm Biomed Anal.2018 Mar 20;J Ethnopharmacol. 2016 Jul 12.The Korea Society of Pharmacognosy.2014Int J Mol Sci.2015 Jan 6;16(1):1232-51.Antiviral Res.2013 Jun;98(3):386-93.
Molecules 2016, 21(6), 780; 2016 Jun 17;21(6).Int J Mol Sci. 2014 May 13;15(5):8443-57.J. Acta Agr. Scandinavica17 Apr 2017International Journal of Mol. Med.2015 Mar 6.Univ. of Limpopo2016
Food Chem.2018 Jun 30;Evid Based Complement Alternat Med. 2017Naunyn Schmiedebergs Arch Pharmacol. 2017 Jul 21. Evidence-Based Comp. & Alter. Med.Dec. 27, 2015
Our products had been exported to the following research institutions and universities, And still growing.
Massachusetts General Hospital (USA)University of Amsterdam (Netherlands)Universiti Putra Malaysia(UPM) (Malaysia)University of Maryland (USA)
Sanford Burnham Medical Research... (USA)Almansora University (Egypt)Nicolaus Copernicus Uniwersity (Poland)National Research Council of Can... (Canada)
Universidade Federal de Santa Ca... (Brazil)University of Fribourg (Switzerland)Stanford University (USA)
||The herbs of Mangifera indica
|Biological Activity or Inhibitors:
||1. 1,5,6-Trihydroxy-3-methoxyxanthone exhibits scavenging activity at 10 uM, it can reduce the viability of HL-60 cells significantly with IC50 values of 28.9 uM.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
1,5,6-Trihydroxy-3-methoxyxanthone References Information
Food Science & Biotechnology, 2013, 22(4):945-949.
|Isolation of xanthones from adventitious roots of St. John’s Wort (Hypericum perforatum L.) and their antioxidant and cytotoxic activities.[Reference: WebLink]|
|In this phytochemical study, 5 xanthones, 1,3,5,6-tetrahydroxyxanthone , 1,5,6-Trihydroxy-3-methoxyxanthone , ferrxanthone , brasilixanthone B , and neolancerin  were isolated from adventitious roots of St. John’s wort (Hypericum perforatum L.). Compound 1–5 were evaluated for antioxidant activities using the intracellular reactive oxygen species (ROS) radical scavenging 2′,7′-dichlorfluorescein-diacetate (DCFDA) assay and for cytotoxic activity against the HL-60 human promyelocytic leukemia cells. Among them, compound 1–4 exhibited scavenging activity with inhibition values of 27.4–33.2% at 10 μM; compound 1, 2, and 4 reduced the viability of HL-60 cells significantly, with IC50 values of 31.5, 28.9, and 27.7 μM, respectively.