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1-Cinnamoyl-3-hydroxypyrrolidine
1-Cinnamoyl-3-hydroxypyrrolidine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1-Cinnamoyl-3-hydroxypyrrolidine
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CAS No.: 1344876-77-2
Catalog No.: CFN96229
Molecular Formula: C13H15NO2
Molecular Weight: 217.3 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Piper nigrum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 1-Cinnamoyl-3-hydroxypyrrolidine is a natural product from Piper nigrum.
1-Cinnamoyl-3-hydroxypyrrolidine Description
Source: The herbs of Piper nigrum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.6019 mL 23.0097 mL 46.0193 mL 92.0387 mL 115.0483 mL
5 mM 0.9204 mL 4.6019 mL 9.2039 mL 18.4077 mL 23.0097 mL
10 mM 0.4602 mL 2.301 mL 4.6019 mL 9.2039 mL 11.5048 mL
50 mM 0.092 mL 0.4602 mL 0.9204 mL 1.8408 mL 2.301 mL
100 mM 0.046 mL 0.2301 mL 0.4602 mL 0.9204 mL 1.1505 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Planta Med. 2017 Jan;83(1-02):143-50.
Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum.[Pubmed: 27405106]

METHODS AND RESULTS:
Sixty-three amide alkaloids, including three new, piperflaviflorine A (1), piperflaviflorine B (2), and sarmentamide D (4), and two previously synthesized ones, (1E,3S)-1-Cinnamoyl-3-hydroxypyrrolidine (3) and N-[7'-(4'-methoxyphenyl)ethyl]-2-methoxybenzamide (5), were isolated from the aerial parts of Piper flaviflorum and Piper sarmentosum. Their structures were elucidated by detailed spectroscopic analysis and, in case of 3, by single-crystal X-ray diffraction. Most of the isolates were tested for their antifungal and antibacterial activities.
CONCLUSIONS:
Ten amides (6-15) showed antifungal activity against Cryptococcus neoformans ATCC 90 113 with IC50 values in the range between 4.7 and 20.0 μg/mL.
Hyperoside

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L-Nicotine

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CAS No: 54-11-5
Price: $40/20mg
Acetylshikonin

Catalog No: CFN90523
CAS No: 24502-78-1
Price: $138/20mg
Neoeriocitrin

Catalog No: CFN92304
CAS No: 13241-32-2
Price: $188/20mg
Bakuchalcone

Catalog No: CFN92229
CAS No: 84575-13-3
Price: $ / mg
Ganoderic acid C2

Catalog No: CFN92054
CAS No: 103773-62-2
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Oroxylin A

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CAS No: 480-11-5
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Resibufogenin

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Ursolic acid

Catalog No: CFN97259
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Price: $30/20mg
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