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1-Methyl-2,8-dihydroxy-3-carboxy-9,10-anthraquinone
1-Methyl-2,8-dihydroxy-3-carboxy-9,10-anthraquinone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1-Methyl-2,8-dihydroxy-3-carboxy-9,10-anthraquinone
Price: $338 / 5mg
CAS No.: 1401414-53-6
Catalog No.: CFN95101
Molecular Formula: C16H10O6
Molecular Weight: 298.3 g/mol
Purity: >=98%
Type of Compound: Anthraquinones
Physical Desc.: Powder
Source: The roots of Rheum palmatum L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Description: Reference standards.
1-Methyl-2,8-dihydroxy-3-carboxy-9,10-anthraquinone Description
Source: The roots of Rheum palmatum L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3523 mL 16.7616 mL 33.5233 mL 67.0466 mL 83.8082 mL
5 mM 0.6705 mL 3.3523 mL 6.7047 mL 13.4093 mL 16.7616 mL
10 mM 0.3352 mL 1.6762 mL 3.3523 mL 6.7047 mL 8.3808 mL
50 mM 0.067 mL 0.3352 mL 0.6705 mL 1.3409 mL 1.6762 mL
100 mM 0.0335 mL 0.1676 mL 0.3352 mL 0.6705 mL 0.8381 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chinese Journal of Natural Medicines, 2011, 9(6):410-413.
Two New Compounds from the Roots of Rheum palmatum.[Reference: WebLink]
To study the constituents of Rheum palmatum.
METHODS AND RESULTS:
Chromatographic separations of silica gel and polyamide were used. All the structures were elucidated on the basis of chemical and spectroscopic analysis. Nine compounds were isolated and their structure were identified as 2, 5-dimethyl-6, 8-dihydroxy-chromone (1), 1-methyl-2, 8-dihydroxy- 3-carboxy −9, 10-anthraquinone (2), citreorosein (3), 4-(4-hydroxyphenyl)-2-butanone (4), 4-(4-hydroxyphenyl)-2-butanone-4′-O-β-D- (2″-galloyl-6″-O-p-coumaroyl)-glucopyranoside (5), trans-3, 5, 4′-trihydroxystilbene-4′-O-β-D-(6″-galloyl)-glucopyranoside (6), 4-(4- hydroxyphenyl)-2-butanone-4′-O-β-D-(6″-O-cinnamoyl)-glucopyranoside (7), 4-(4-hydroxyphenyl)-2-butanone-4′-O-β-D-(6″-O-p-coumaroyl)-glucopyranoside (8), trans-3, 5, 4′-trihydroxystilbene-4′-O-β-D-glucopyranoside (9).
CONCLUSIONS:
Compounds 1 and 2 were newly isolated from Rheum palmatum.
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