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    12-Epinapelline
    12-Epinapelline
    Information
    CAS No. 110064-71-6 Price $318 / 20mg
    Catalog No.CFN90663Purity>=98%
    Molecular Weight359.5Type of CompoundAlkaloids
    FormulaC22H33NO3Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: 12-Epinapelline is a natural product from Aconitum kusnezoffii Reichb.
    12-Epinapelline Description
    Source: The roots of Aconitum kusnezoffii Reichb.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.7816 mL 13.9082 mL 27.8164 mL 55.6328 mL 69.541 mL
    5 mM 0.5563 mL 2.7816 mL 5.5633 mL 11.1266 mL 13.9082 mL
    10 mM 0.2782 mL 1.3908 mL 2.7816 mL 5.5633 mL 6.9541 mL
    50 mM 0.0556 mL 0.2782 mL 0.5563 mL 1.1127 mL 1.3908 mL
    100 mM 0.0278 mL 0.1391 mL 0.2782 mL 0.5563 mL 0.6954 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Chemistry of Natural Compounds, 2005,41(5):609.
    Crystal and Molecular Structure of 12-Epinapelline[Reference: WebLink]

    METHODS AND RESULTS:
    The article examines the crystal and molecular structure of 12-Epinapelline. Previous investigations showed that the conformation of ring A in crystal structures of napelline-type alkaloids depended on the presence or absence of an intramolecular H-bond between an alpha-oriented C1 hydroxyl and the N atom.
    CONCLUSIONS:
    Thus, ring A in 12-epilucidusculin had the boat conformation and in acophine it adopted the twist or chair conformation.