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12-Hydroxysapriparaquinone
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Product Name 12-Hydroxysapriparaquinone
Price:
CAS No.: 142763-37-9
Catalog No.: CFN92244
Molecular Formula: C20H24O3
Molecular Weight: 312.4 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The roots of Salvia prionitis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 12-Hydroxysapriparaquinone is a natural product from Salvia prionitis.
In vivo:
Records of Natural Products, 2007 , 1 (1) :1-16.
Biological activity of diterpenoids isolated from Anatolian Lamiaceae Plants[Reference: WebLink]

METHODS AND RESULTS:
Since Salvia species, especially Chinese sage S. milthiorrhiza has been used in the treatment of coronary heart diseases, Prof. Ulubelen group also investigated cardiovascular properties of several Salvia extracts (S. amplexicaulis, S. eriophora and S. syriaca) and their constituents in vivo, on Wistar Albino rats [5, 40-42]. The crude extract of S. eriophora and isolated eleven diterpenoids ferruginol (11), aethiopinone (56), 4,12-dihydroxysapriparaquinone (63), 6,7-didehydroroyleanone (64) and 4,14-dihydroxysaprorthoquinone (65), horminone, acetylhorminone, salvipisone, 12-Hydroxysapriparaquinone, 3,12-dihydroxysapri-paraquinone-1-ene, salvilimbinol, were tested [40] for cardiovascular activity.
CONCLUSIONS:
Among the tested abietanes, compounds 65, 56, 11, 63 and 64 as well as the crude extract showed antihypertensive activity, especially ferruginol, aethiopinone and 4,12- dihydroxysapriparaquinone by significantly reducing arterial blood pressure, and this activity is considered probably due to the vasorelaxation activity [5].
12-Hydroxysapriparaquinone Description
Source: The roots of Salvia prionitis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.201 mL 16.0051 mL 32.0102 mL 64.0205 mL 80.0256 mL
5 mM 0.6402 mL 3.201 mL 6.402 mL 12.8041 mL 16.0051 mL
10 mM 0.3201 mL 1.6005 mL 3.201 mL 6.402 mL 8.0026 mL
50 mM 0.064 mL 0.3201 mL 0.6402 mL 1.2804 mL 1.6005 mL
100 mM 0.032 mL 0.1601 mL 0.3201 mL 0.6402 mL 0.8003 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Oroxylin A

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CAS No: 480-11-5
Price: $80/20mg
6beta-Hydroxystigmast-4-en-3-one

Catalog No: CFN98496
CAS No: 36450-02-9
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Isovalerylshikonin

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