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    14-Deoxy-17-hydroxyandrographolide
    Information
    CAS No. 869384-82-7 Price
    Catalog No.CFN97601Purity>=98%
    Molecular Weight352.47Type of CompoundDiterpenoids
    FormulaC20H32O5Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    10 mM * 1 mL in DMSO / Inquiry / In-stock
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    Description: Standard reference
    Targets: Antifection
    14-Deoxy-17-hydroxyandrographolide Description
    Source: The herbs of Andrographis paniculata (Burm. f.) Nees
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

    PMID: 29328914

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    IF=22.415(2019)

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    IF=14.548(2019)

    PMID: 29149595

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    IF=13.903(2019)

    PMID: 29553709

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    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

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    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8371 mL 14.1856 mL 28.3712 mL 56.7424 mL 70.928 mL
    5 mM 0.5674 mL 2.8371 mL 5.6742 mL 11.3485 mL 14.1856 mL
    10 mM 0.2837 mL 1.4186 mL 2.8371 mL 5.6742 mL 7.0928 mL
    50 mM 0.0567 mL 0.2837 mL 0.5674 mL 1.1348 mL 1.4186 mL
    100 mM 0.0284 mL 0.1419 mL 0.2837 mL 0.5674 mL 0.7093 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Nat Prod. 2006 Mar;69(3):319-22.
    ent-Labdane diterpenoids from Andrographis paniculata.[Pubmed: 16562826]

    METHODS AND RESULTS:
    Six new ent-labdane diterpenoids, 3-O-beta-D-glucopyranosyl-14,19-dideoxyandrographolide (1), 14-Deoxy-17-hydroxyandrographolide (2), 19-O-[beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranoyl]-3,14-dideoxyandrographolide (3), 3-O-beta-d-glucopyranosylandrographolide (4), 12S-hydroxyandrographolide (5), and andrographatoside (6), together with 17 known analogues, were isolated from the aerial parts of Andrographis paniculata. The structures of 1-6 were determined by spectroscopic data analysis. All compounds isolated were evaluated for their inhibitory activity against several bacterial and fungal strains.