|Source:||The sclerotium of Poria cocos(Schw.)Wolf|
|Biological Activity or Inhibitors:|| 1. 16 alpha-Hydroxytrametenolic acid can inhibit 12-O-tetradecanoylphorbol 13-acetate (TAP)-induced mouse ear edema.
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.1155 mL||10.5775 mL||21.1551 mL||42.3101 mL||52.8877 mL|
|5 mM||0.4231 mL||2.1155 mL||4.231 mL||8.462 mL||10.5775 mL|
|10 mM||0.2116 mL||1.0578 mL||2.1155 mL||4.231 mL||5.2888 mL|
|50 mM||0.0423 mL||0.2116 mL||0.4231 mL||0.8462 mL||1.0578 mL|
|100 mM||0.0212 mL||0.1058 mL||0.2116 mL||0.4231 mL||0.5289 mL|
Chem Pharm Bull (Tokyo). 1996 Apr;44(4):847-9.
|Isolation of inhibitors of TPA-induced mouse ear edema from Hoelen, Poria cocos.[Pubmed: 8681415]|
|Triterpene carboxylic acids were isolated from the methanol extract of Hoelen, Poria cocos, and found to inhibit 12-O-tetradecanoylphorbol 13-acetate (TAP)-induced mouse ear edema. Their chemical structures were identified as 3 beta,-16 alpha-dihydroxylanosta-7,9(11),24-trien-21-oic acid, 16 alpha-hydroxydehydropachymic acid, 16 alpha-Hydroxytrametenolic acid and dehydrotumulosic acid.|