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2-Hydroxydiplopterol
2-Hydroxydiplopterol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 2-Hydroxydiplopterol
Price:
CAS No.: 1193250-54-2
Catalog No.: CFN96988
Molecular Formula: C30H52O2
Molecular Weight: 444.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The metabolites of the fungal strain Aspergillus variecolor B-17.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 2-Hydroxydiplopterol exhibits cytotoxicity against K562 cells with an IC50 value of 22 microM.
In vitro:
Arch Pharm Res. 2009 Sep;32(9):1211-4.
2-Hydroxydiplopterol, a new cytotoxic pentacyclic triterpenoid from the halotolerant fungus Aspergillus variecolor B-17.[Pubmed: 19784575]

METHODS AND RESULTS:
A new hopane type pentacyclic triterpenoid, 2-Hydroxydiplopterol (1) has been isolated from the metabolites produced by the halotolerant fungal strain Aspergillus variecolor B-17. The structure of 1 was determined by spectroscopic methods and single crystal X-Ray diffraction analysis.
CONCLUSIONS:
2-Hydroxydiplopterol (1) exhibited cytotoxicity against K562 cells with an IC50 value of 22 microM.
2-Hydroxydiplopterol Description
Source: The metabolites of the fungal strain Aspergillus variecolor B-17.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2487 mL 11.2435 mL 22.4871 mL 44.9741 mL 56.2177 mL
5 mM 0.4497 mL 2.2487 mL 4.4974 mL 8.9948 mL 11.2435 mL
10 mM 0.2249 mL 1.1244 mL 2.2487 mL 4.4974 mL 5.6218 mL
50 mM 0.045 mL 0.2249 mL 0.4497 mL 0.8995 mL 1.1244 mL
100 mM 0.0225 mL 0.1124 mL 0.2249 mL 0.4497 mL 0.5622 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN97985Hopane-3beta,22-diol22149-65-1444.7C30H52O2
CFN98222Zeorin22570-53-2444.7 C30H52O2
CFN97469Sorghumol90582-44-8426.7 C30H50O
CFN97470Sorghumol acetate90582-47-1468.8 C32H52O2
CFN99393Rubiarbonol B130288-60-7458.7 C30H50O3
CFN99678Simiarenol1615-94-7426.7 C30H50O
CFN98790Simiarenol acetate4965-99-5468.8 C32H52O2
CFN98239Simiarenone2318-78-7424.7 C30H48O
CFN98944Hop-17(21)-en-3-ol564-14-7426.7 C30H50O
CFN8911119alpha-Hydroxyfern-7-ene70588-12-4426.72C30H50O
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