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24-Methylenecycloartanone
24-Methylenecycloartanone
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Product Name 24-Methylenecycloartanone
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CAS No.: 1449-08-7
Catalog No.: CFN96941
Molecular Formula: C31H50O
Molecular Weight: 438.74 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The rhizomes of Polygonum bistorta.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Description: 24-Methylenecycloartanone is a natural product from Polygonum bistorta.
24-Methylenecycloartanone Description
Source: The rhizomes of Polygonum bistorta.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2793 mL 11.3963 mL 22.7925 mL 45.5851 mL 56.9814 mL
5 mM 0.4559 mL 2.2793 mL 4.5585 mL 9.117 mL 11.3963 mL
10 mM 0.2279 mL 1.1396 mL 2.2793 mL 4.5585 mL 5.6981 mL
50 mM 0.0456 mL 0.2279 mL 0.4559 mL 0.9117 mL 1.1396 mL
100 mM 0.0228 mL 0.114 mL 0.2279 mL 0.4559 mL 0.5698 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry. 2005 Oct;66(19):2304-8.
Cycloartane type triterpenoids from the rhizomes of Polygonum bistorta.[Pubmed: 16112695 ]

METHODS AND RESULTS:
Two new compounds, 24(E)-ethylidenecycloartanone (1) and 24(E)-ethylidenecycloartan-3alpha-ol (2) were isolated from the rhizomes of Polygonum bistorta, together with seven known compounds viz., cycloartane-3,24-dione (3), 24-Methylenecycloartanone (4), gamma-sitosterol (5), beta-sitosterol (6), beta-sitosterone (7), friedelin (8) and 3beta-friedelinol (9).
CONCLUSIONS:
All the cycloartane type triterpenoids, compounds 7 and 8 are reported for the first time from this plant. A combination of 1D and 2D NMR spectroscopy and MS were mainly used to elucidate the structures of the new compounds 1 and 2.
CFN97994Cycloartanol4657-58-3428.7C30H52O
CFN9949624-Methylenecycloartan-3-ol1449-09-8440.8 C31H52O
CFN9937024-Methylenecycloartanol acetate1259-94-5482.8 C33H54O2
CFN9177824-Methylene cycloartanyl ferulate469-36-3616.91C41H60O4
CFN9694124-Methylenecycloartanone1449-08-7438.74C31H50O
CFN9787824-Methylenecycloartane-3beta,26-diol17020-27-8456.8C31H52O2
CFN9807423-deoxojessic acid215609-93-1486.7 C31H50O4
CFN996191-Dehydroxy-23-deoxojessic acid149252-87-9470.7 C31H50O3
CFN98701Cycloeucalenol469-39-6426.7 C30H50O
CFN97763Cyclomusalenone30452-60-9424.71C30H48O
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