Science | Nature | Cell | View More
Natural Products
27-p-Coumaroyloxyursolic acid
27-p-Coumaroyloxyursolic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 27-p-Coumaroyloxyursolic acid
Price:
CAS No.: 73584-67-5
Catalog No.: CFN97217
Molecular Formula: C39H54O6
Molecular Weight: 618.9 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Viburnum cylindricum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Texas A&M University (USA)
  • Weizmann Institute of Science (Israel)
  • Sant Gadge Baba Amravati Univer... (India)
  • Nanjing University of Chinese M... (China)
  • University of Mysore (India)
  • Indian Institute of Science (India)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • University of Dicle (Turkey)
  • Universidade de Franca (Brazil)
  • Warszawski Uniwersytet Medyczny (Poland)
  • Shanghai University of TCM (China)
  • More...
Package
Featured Products
Phellodendrine

Catalog No: CFN99143
CAS No: 6873-13-8
Price: $90/20mg
Timosaponin A3

Catalog No: CFN98151
CAS No: 41059-79-4
Price: $50/20mg
Luteolin-3-O-beta-D-glucuronide

Catalog No: CFN93187
CAS No: 53527-42-7
Price: $238/10mg
Platycodin D3

Catalog No: CFN93272
CAS No: 67884-03-1
Price: $318/10mg
Neochlorogenic acid

Catalog No: CFN97472
CAS No: 906-33-2
Price: $90/20mg
Cinnamaldehyde

Catalog No: CFN99478
CAS No: 104-55-2
Price: $30/20mg
Schisandrol A

Catalog No: CFN99012
CAS No: 7432-28-2
Price: $30/20mg
Oxypeucedanin

Catalog No: CFN90350
CAS No: 737-52-0
Price: $80/20mg
Astragaloside II

Catalog No: CFN99173
CAS No: 84676-89-1
Price: $50/20mg
Cantharidin

Catalog No: CFN99790
CAS No: 56-25-7
Price: $40/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 27-trans-p-Coumaroyloxyursolic acid and 27-cis-p-coumaroyloxyursolic acid show potent inhibitory activity in the acyl CoA cholesteryl acyl transferase (ACAT) assay.
In vitro:
J Nat Prod. 1999 Jul;62(7):1061-4.
Activity-guided isolation of triterpenoid acyl CoA cholesteryl acyl transferase (ACAT) inhibitors from Ilex kudincha.[Pubmed: 10425145 ]

METHODS AND RESULTS:
Activity-guided fractionation of a methanol extract of the leaves of Ilex kudincha led to the isolation of seven acyl CoA cholesteryl acyl transferase (ACAT) inhibitory triterpenes. Four of them were identified by spectroscopic methods as ulmoidol (4), 23-hydroxyursolic acid (5), 27-trans-p-coumaroyloxyursolic acid (6), and 27-cis-p-coumaroyloxyursolic acid (7), and three were new compounds named ilekudinols A-C (1-3). The structures of these new triterpenoids were elucidated as 2alpha, 3beta-dihydroxy-24-nor-urs-4(23),11-dien-28,13beta- olide (1), 2alpha, 3beta-dihydroxy-24-nor-urs-4(23),12-dien-28-oic acid (2), and 3beta, 24,28-trihydroxylupane (3).
CONCLUSIONS:
Compounds 1-7 showed potent inhibitory activity in the ACAT assay.
27-p-Coumaroyloxyursolic acid Description
Source: The herbs of Viburnum cylindricum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Methyl 2-hydroxy-3,4-dimethoxybenz...

Catalog No: CFN95383
CAS No: 6395-23-9
Price: $268/5mg
3'-Angeloyloxy-4'-senecioyloxy-2',...

Catalog No: CFN95123
CAS No: 1221686-60-7
Price: $398/5mg
5-Demethylsinensetin

Catalog No: CFN95415
CAS No: 21763-80-4
Price: $318/10mg
New compound 20

Catalog No: CFN95545
CAS No: N/A
Price: $413/5mg
Euphorbia factor L25

Catalog No: CFN95339
CAS No: 303174-98-3
Price: $368/5mg
Polygalacin D2

Catalog No: CFN95241
CAS No: 66663-92-1
Price: $413/5mg
Lucidenic acid D2

Catalog No: CFN95020
CAS No: 98665-16-8
Price: $268/5mg
3'-O-Methylviolanone

Catalog No: CFN95387
CAS No: 56973-42-3
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6158 mL 8.0788 mL 16.1577 mL 32.3154 mL 40.3942 mL
5 mM 0.3232 mL 1.6158 mL 3.2315 mL 6.4631 mL 8.0788 mL
10 mM 0.1616 mL 0.8079 mL 1.6158 mL 3.2315 mL 4.0394 mL
50 mM 0.0323 mL 0.1616 mL 0.3232 mL 0.6463 mL 0.8079 mL
100 mM 0.0162 mL 0.0808 mL 0.1616 mL 0.3232 mL 0.4039 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Planta Med. 2001 Oct;67(7):683-4.
Sterols, triterpenes and biflavonoids of Viburnum jucundum and cytotoxic activity of ursolic acid.[Pubmed: 11582553 ]

METHODS AND RESULTS:
The triterpenes ursolic acid (1), 27-p-Z-coumaroyloxyursolic acid (2), 27-p-E-coumaroyloxyursolic acid, alpha-amyrine-3-palmitate and lupeol-3-palmitate were isolated through a bioactivity-guided fractionation from the acetonic extract of the aerial parts of Viburnum jucundum Morton in addition to amentoflavone, an epimeric mixture at C-2 of 2,3-dihydroamentoflavone, beta-sitosterol and beta-sitosteryl glucopyranoside.
CONCLUSIONS:
Ursolic acid (1) was the only constituent that exhibited cytotoxic activity toward three human cancer cell lines in culture. This is the first phytochemical and cytotoxic analysis performed to this plant species.
Phellodendrine

Catalog No: CFN99143
CAS No: 6873-13-8
Price: $90/20mg
Timosaponin A3

Catalog No: CFN98151
CAS No: 41059-79-4
Price: $50/20mg
Luteolin-3-O-beta-D-glucuronide

Catalog No: CFN93187
CAS No: 53527-42-7
Price: $238/10mg
Platycodin D3

Catalog No: CFN93272
CAS No: 67884-03-1
Price: $318/10mg
Neochlorogenic acid

Catalog No: CFN97472
CAS No: 906-33-2
Price: $90/20mg
Cinnamaldehyde

Catalog No: CFN99478
CAS No: 104-55-2
Price: $30/20mg
Schisandrol A

Catalog No: CFN99012
CAS No: 7432-28-2
Price: $30/20mg
Oxypeucedanin

Catalog No: CFN90350
CAS No: 737-52-0
Price: $80/20mg
Astragaloside II

Catalog No: CFN99173
CAS No: 84676-89-1
Price: $50/20mg
Cantharidin

Catalog No: CFN99790
CAS No: 56-25-7
Price: $40/20mg
Tags: buy 27-p-Coumaroyloxyursolic acid | 27-p-Coumaroyloxyursolic acid supplier | purchase 27-p-Coumaroyloxyursolic acid | 27-p-Coumaroyloxyursolic acid cost | 27-p-Coumaroyloxyursolic acid manufacturer | order 27-p-Coumaroyloxyursolic acid | 27-p-Coumaroyloxyursolic acid distributor