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3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan
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Product Name 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan
Price:
CAS No.: 873867-94-8
Catalog No.: CFN96935
Molecular Formula: C22H24O7
Molecular Weight: 400.42 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The roots of Artemisia absinthium.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Description: Reference standards.
In vitro:
Pharmaceutical Biology, 2008, 43(4):378-381.
A New Larvicidal Lignan from Piper fimbriulatum.[Reference: WebLink]

METHODS AND RESULTS:
A new lignan, 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan (1) (6-[4-(3,4-dimethoxy-phenyl)-tetrahydro-furo[3,4-c.]furan-1-yl]-4-methoxy-benzo[] dioxole) together with two known lignans, 7′-epi.-sesartemin (2) and diayangambin (3), and a known flavonoid, 5-hydroxy-7,4′-dimethoxyflavone (4), were isolated from the leaves of Piper fimbriulatum. C. DC. Their structures were assigned by a combination of one- and two-dimensional NMR techniques.
CONCLUSIONS:
7′-epi.-Sesartemin (2) showed the highest larvicidal activity against Aedes aegypti. (LC100 17.6 µg/ml) and weak antiplasmodial (IC50 7.0 µg/ml) and antitrypanosomal (IC50 39.0 µg/ml) activities. None of the compounds was active against Leishmania mexicana..
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan Description
Source: The roots of Artemisia absinthium.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4974 mL 12.4869 mL 24.9738 mL 49.9476 mL 62.4344 mL
5 mM 0.4995 mL 2.4974 mL 4.9948 mL 9.9895 mL 12.4869 mL
10 mM 0.2497 mL 1.2487 mL 2.4974 mL 4.9948 mL 6.2434 mL
50 mM 0.0499 mL 0.2497 mL 0.4995 mL 0.999 mL 1.2487 mL
100 mM 0.025 mL 0.1249 mL 0.2497 mL 0.4995 mL 0.6243 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Oleanolic acid

Catalog No: CFN98800
CAS No: 508-02-1
Price: $30/20mg
Ganoderic acid K

Catalog No: CFN92057
CAS No: 104700-95-0
Price: $318/5mg
Butein

Catalog No: CFN98776
CAS No: 487-52-5
Price: $100/20mg
Eriodictyol

Catalog No: CFN99719
CAS No: 552-58-9
Price: $128/20mg
Isoastragaloside I

Catalog No: CFN90977
CAS No: 84676-88-0
Price: $268/10mg
Ginsenoside Re

Catalog No: CFN99974
CAS No: 52286-59-6
Price: $40/20mg
Matrine

Catalog No: CFN98835
CAS No: 519-02-8
Price: $30/20mg
Glycyrrhetinic acid

Catalog No: CFN99152
CAS No: 471-53-4
Price: $30/20mg
5-Hydroxymethylfurfural

Catalog No: CFN97149
CAS No: 67-47-0
Price: $40/20mg
Diosmin

Catalog No: CFN98145
CAS No: 520-27-4
Price: $30/20mg
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