3',4',5'-Trimethoxyflavone | CAS:67858-30-4

3',4',5'-Trimethoxyflavone

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Description:

The 3',4',5-trimethoxyflavone derivative and its pharmaceutically acceptable salt inhibit corneal damage through excellent stimulatory action on mucus secretion in the conjunctiva and therefore may be effective as a prophylactic or therapeutic agent for dry eye syndrome.

In vitro:

CN20088019063 on 02 Jun 2008

3',4',5-trimethoxy flavone derivatives as stimulant of mucus secretion, method of the same, and pharmaceutical composition comprising the same.[Reference: WebLink]

METHODS AND RESULTS:
The present invention provides a 3',4',5-Trimethoxyflavone derivative(3',4',5'-Trimethoxyflavone) and a pharmaceutically acceptable salt thereof, preparation thereof, and a pharmaceutical composition for the treatment and prevention of dry eye syndrome comprising the same as an active ingredient.
CONCLUSIONS:
The 3',4',5-trimethoxyflavone derivative and its pharmaceutically acceptable salt inhibit corneal damage through excellent stimulatory action on mucus secretion in the conjunctiva and therefore may be effective as a prophylactic or therapeutic agent for dry eye syndrome.

3',4',5'-Trimethoxyflavone Description

Source:	The herbs of Centaurea scoparia
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	3',4',5'-Trimethoxyflavone
Price:	$118 / 10mg
CAS No.:	67858-30-4
Catalog No.:	CFN70439
Molecular Formula:	C₁₈H₁₆O₅
Molecular Weight:	312.3 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Centaurea scoparia
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.202 mL	16.0102 mL	32.0205 mL	64.041 mL	80.0512 mL
5 mM	0.6404 mL	3.202 mL	6.4041 mL	12.8082 mL	16.0102 mL
10 mM	0.3202 mL	1.601 mL	3.202 mL	6.4041 mL	8.0051 mL
50 mM	0.064 mL	0.3202 mL	0.6404 mL	1.2808 mL	1.601 mL
100 mM	0.032 mL	0.1601 mL	0.3202 mL	0.6404 mL	0.8005 mL

CFN98076	3',4',5',3,5,7,8-Heptamethoxyflavone	21634-52-6	432.4	C₂₂H₂₄O₉
CFN90998	8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone	1000415-56-4	418.39	C₂₁H₂₂O₉
CFN91804	Natsudaidain	35154-55-3	418.4	C₂₁H₂₂O₉
CFN99812	3',4',5',3,5,6,7-Heptamethoxyflavone	17245-30-6	432.4	C₂₂H₂₄O₉
CFN70469	5,7-Dihydroxy 3,3',4',5',6,8-hexamethoxyflavone	96887-18-2	434.4	C₂₁H₂₂O₁₀
CFN99417	Exoticin	13364-94-8	462.5	C₂₃H₂₆O₁₀
CFN97489	Viscidulin I	92519-95-4	302.2	C₁₅H₁₀O₇
CFN98780	Robinetin	490-31-3	302.2	C₁₅H₁₀O₇
CFN98877	Myricetin	529-44-2	318.2	C₁₅H₁₀O₈
CFN96262	Mearnsetin	16805-10-0	332.3	C₁₆H₁₂O₈