• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    4,4'-Methylenediphenol
    Information
    CAS No. 620-92-8 Price $30 / 20mg
    Catalog No.CFN90549Purity>=98%
    Molecular Weight200.23Type of CompoundPhenols
    FormulaC13H12O2Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    Our products had been exported to the following research institutions and universities, And still growing.
  • Michigan State University (USA)
  • Korea Intitute of Science and Te... (Korea)
  • University of Mysore (India)
  • Charles University in Prague (Czech Republic)
  • Anna University (India)
  • Universidad de Antioquia (Colombia)
  • Universitas Airlangga (Indonesia)
  • University of Dicle (Turkey)
  • Agricultural Research Organizati... (Israel)
  • The Australian National University (Australia)
  • Korea Food Research Institute(KF... (Korea)
  • More...
  • Package
    Featured Products
    2,4'-Dihydroxybenzophenone

    Catalog No: CFN92400
    CAS No: 606-12-2
    Price: $40/20mg
    Wogonoside

    Catalog No: CFN99710
    CAS No: 51059-44-0
    Price: $100/20mg
    Ganoderic acid DM

    Catalog No: CFN99815
    CAS No: 173075-45-1
    Price: $592/5mg
    Chrysosplenol D

    Catalog No: CFN99622
    CAS No: 14965-20-9
    Price: $268/10mg
    Mulberrofuran H

    Catalog No: CFN92414
    CAS No: 89199-99-5
    Price: $533/5mg
    Biological Activity
    Description: 4,4'-Methylenediphenol is a high purity product from Gastrodia rhizome.
    In vitro:
    Biomed Chromatogr. 2016 Jun;30(6):976-82.
    Preparative purification of plasmin activity stimulating phenolic derivatives from Gastrodia elata using centrifugal partition chromatography.[Pubmed: 26517716 ]
    Gastrodia rhizome, a dried and steamed tuber of Gastrodia elata Blume (Orchidaceae), has been traditionally used in Korea, China and Japan for the treatment of neurological and nervous disorders such as headaches, dizziness, vertigo and convulsive illnesses. The ethyl acetate and water extracts of G. elata stimulated plasmin activity.
    METHODS AND RESULTS:
    The active ethyl acetate fraction was subjected to centrifugal partition chromatography (CPC) with a two-phase solvent system, composed of n-hexane-ethyl acetate-methanol-water (3:7:4:6, v/v) followed by semi-preparative HPLC purification to separate active compounds and the water fraction was purified by Diaion HP-20 resin and semi-preparative HPLC. In ethyl acetate extract, 4-hydroxybenzyl alcohol (1), 4-hydroxybenzoic acid (2), 4-hydroxybenzaldehyde (3), 4-ethoxymethylphenol (4), 4,4'-oxybis(methylene)diphenol (5) and 4,4'-Methylenediphenol (6) were obtained with high purities. Parishin (7) and parishin B (8) were isolated from water extract.
    CONCLUSIONS:
    Among isolated compounds, 4-hydroxybenzyl alcohol (1), 4-hydroxybenzaldehyde (3) and 4-ethoxymethylphenol (4) significantly stimulated plasmin activity.
    4,4'-Methylenediphenol Description
    Source: The tubers of Gastrodia elata Blume.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    1,3,6-Tri-O-galloylglucose

    Catalog No: CFN95043
    CAS No: 18483-17-5
    Price: $338/10mg
    Ganoderenic acid D

    Catalog No: CFN90300
    CAS No: 100665-43-8
    Price: $476/10mg
    Ginsenoside Rh4

    Catalog No: CFN92594
    CAS No: 174721-08-5
    Price: $368/10mg
    Carasinol B

    Catalog No: CFN95042
    CAS No: 777857-86-0
    Price: $333/5mg
    Magnoloside A

    Catalog No: CFN99232
    CAS No: 113557-95-2
    Price: $318/5mg
    Bryonamide B

    Catalog No: CFN91057
    CAS No: 5942-25-6
    Price: $218/5mg
    Orcinol 1-O-beta-D-apiofuranosyl-(...

    Catalog No: CFN95109
    CAS No: 868557-54-4
    Price: $338/5mg
    Yadanzioside G

    Catalog No: CFN96422
    CAS No: 95258-17-6
    Price: $413/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.9943 mL 24.9713 mL 49.9426 mL 99.8851 mL 124.8564 mL
    5 mM 0.9989 mL 4.9943 mL 9.9885 mL 19.977 mL 24.9713 mL
    10 mM 0.4994 mL 2.4971 mL 4.9943 mL 9.9885 mL 12.4856 mL
    50 mM 0.0999 mL 0.4994 mL 0.9989 mL 1.9977 mL 2.4971 mL
    100 mM 0.0499 mL 0.2497 mL 0.4994 mL 0.9989 mL 1.2486 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.