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5-Hydroxyseselin
5-Hydroxyseselin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 5-Hydroxyseselin
Price:
CAS No.: 31525-75-4
Catalog No.: CFN92512
Molecular Formula: C14H12O4
Molecular Weight: 244.2 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Cryst.
Source: The roots of Toddalia asiatica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
J Nat Prod. 2005 Jan;68(1):78-82.
Natural and synthetic 2,2-dimethylpyranocoumarins with antibacterial activity.[Pubmed: 15679322]

METHODS AND RESULTS:
A new efficient synthetic approach to the natural coumarins 5-Hydroxyseselin (5), 5-methoxyseselin (3), and (+/-) cis-grandmarin (9) is described as well as the synthesis of some new derivatives in the 5-methoxyseselin series (10-15). The natural coumarins 7-hydroxyalloxanthyletin (6), alloxanthoxyletin (8), and dipetalolactone (7) have also been obtained as secondary products. The type of fusion of the pyrano ring in all cases has been established by 2D NMR spectroscopy.
CONCLUSIONS:
The compounds have been studied for their in vitro antibacterial activity, which has been compared with that of some previously synthesized seselin derivatives. The most active compounds were 3, 7, 8, 11, and 14. Some structure-activity relationships are discussed.
5-Hydroxyseselin Description
Source: The roots of Toddalia asiatica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

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ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

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Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.095 mL 20.475 mL 40.95 mL 81.9001 mL 102.3751 mL
5 mM 0.819 mL 4.095 mL 8.19 mL 16.38 mL 20.475 mL
10 mM 0.4095 mL 2.0475 mL 4.095 mL 8.19 mL 10.2375 mL
50 mM 0.0819 mL 0.4095 mL 0.819 mL 1.638 mL 2.0475 mL
100 mM 0.041 mL 0.2048 mL 0.4095 mL 0.819 mL 1.0238 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Naringenin

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Momordicine II

Catalog No: CFN95167
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Saikosaponin D

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Lotusine

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2-Hydroxynaringenin

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Irigenin

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Humulone

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Ginsenoside Rb1

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