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6'-O-Cinnamoylharpagide
6'-O-Cinnamoylharpagide
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 6'-O-Cinnamoylharpagide
Price:
CAS No.: 1245572-24-0
Catalog No.: CFN93166
Molecular Formula: C24H30O11
Molecular Weight: 494.49 g/mol
Purity: >=98%
Type of Compound: Iridoids
Physical Desc.: Powder
Source: The roots of Scrophularia ningpoensis Hemsl.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 6'-O-Cinnamoylharpagide has anti-inflammatory activity.
Targets: NO
In vitro:
Planta Medica, 2012, 78(14).
Compounds form the roots of Harpagophytum procumbens and their anti-inflammatory activity.[Reference: WebLink]

METHODS AND RESULTS:
Six known compounds: cinnamic acid (1), harpagoside, (2), 8-O-(cis-cinnamoyl)harpagide (3), acteoside (4), isoacteoside (5), and 6'-O-Cinnamoylharpagide (6) were isolated from the roots of Harpagophytum procumbens. The chemical structures of these compounds were determined on the basis of spectroscopic analyses including 2D NMR. Their anti-inflammatory activity was evaluated against LPS-induced NO production in macrophage RAW264.7 cells.
6'-O-Cinnamoylharpagide Description
Source: The roots of Scrophularia ningpoensis Hemsl.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0223 mL 10.1114 mL 20.2229 mL 40.4457 mL 50.5571 mL
5 mM 0.4045 mL 2.0223 mL 4.0446 mL 8.0891 mL 10.1114 mL
10 mM 0.2022 mL 1.0111 mL 2.0223 mL 4.0446 mL 5.0557 mL
50 mM 0.0404 mL 0.2022 mL 0.4045 mL 0.8089 mL 1.0111 mL
100 mM 0.0202 mL 0.1011 mL 0.2022 mL 0.4045 mL 0.5056 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Nat Prod Res. 2009;23(13):1181-8.
A new iridoid glycoside from Scrophularia ningpoensis.[Pubmed: 19731136]

METHODS AND RESULTS:
A new iridoid glycoside, named 6'-O-Cinnamoylharpagide (1), has been isolated from the roots of Scrophularia ningpoensis (Scrophulariaceae) together with nine known compounds, harpagide (2), harpagoside (3), 8-O-feruloylharpagide (4), 8-O-(p-coumaroyl)harpagide (5), 6-O-methylcatalpol (6), aucubin (7), buergerinin B (8), teuhircoside (9) and 6-O-cinnamoyl-D-glucopyranose (10). Compound 10 was obtained as an inseparable mixture of 6-O-cinnamoyl-alpha-D-glucopyranose and 6-O-cinnamoyl-beta-D-glucopyranose at a ratio of 1 : 1, which is presumably formed by cleavage of compound 1.
CONCLUSIONS:
Their structures were elucidated on the basis of chemical and spectral analysis.
Kurarinone

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Myricanol

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CAS No: 33606-81-4
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Isoliensinine

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Gambogenic acid

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CAS No: 173932-75-7
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Ginsenoside Rb1

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CAS No: 41753-43-9
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Cryptotanshinone

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Estragole

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