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7-Prenyljacareubin
7-Prenyljacareubin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 7-Prenyljacareubin
Price:
CAS No.: 94513-60-7
Catalog No.: CFN89056
Molecular Formula: C23H22O6
Molecular Weight: 394.42 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Powder
Source: The stem barks of Garcinia paucinervis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 7-Prenyljacareubin shows moderate cytotoxic activity against HL-60, SMMC-7721, A549, MCF-7, and SW480 cell lines.
7-Prenyljacareubin Description
Source: The stem barks of Garcinia paucinervis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5354 mL 12.6768 mL 25.3537 mL 50.7074 mL 63.3842 mL
5 mM 0.5071 mL 2.5354 mL 5.0707 mL 10.1415 mL 12.6768 mL
10 mM 0.2535 mL 1.2677 mL 2.5354 mL 5.0707 mL 6.3384 mL
50 mM 0.0507 mL 0.2535 mL 0.5071 mL 1.0141 mL 1.2677 mL
100 mM 0.0254 mL 0.1268 mL 0.2535 mL 0.5071 mL 0.6338 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chinese Traditional & Herbal Drugs, 2012, 43(3):436-439.
Chemical constituents from stem barks of Garcinia paucinervis.[Reference: WebLink]
To study the chemical constituents from the stem barks of Garcinia paucinervis and their antitumor activities.
METHODS AND RESULTS:
Chemical constituents were isolated and purified from petroleum ether extract of G. paucinervis by chromatography on silica gel, RP-18, Sephadex LH-20 column, and preparative TLC. Their structures were identified on the basis of spectroscopic analysis and chemical evidence. The antitumor activity was screened by MTT assay. Ten compounds were isolated and identified as cambogin (1), pyromeconic acid (2), β-sitosterol (3), daucosterol (4), 7-Prenyljacareubin (5), parvifolixanthone A (6), formoxanthone A (7), termicalcicolanone A (8), 1, 3, 5, 6-tetrahydroxy-4-prenylxanthone (9), and isogarcinol (10). Compounds 5 and 7 showed moderate cytotoxic activity against HL-60, SMMC-7721, A549, MCF-7, and SW480 cell lines.
CONCLUSIONS:
Compounds 2-5 and 7-10 are isolated from this plant for the first time and the 13C-NMR spectroscopic data of compound 5 are firstly reported.
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Piceatannol

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Price: $40/20mg
Hirsutenone

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