8-Hydroxy-4-cadinen-3-one | CAS:97372-53-7

8-Hydroxy-4-cadinen-3-one

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Description:

8-Hydroxy-4-cadinen-3-one shows significant inhibitory activity against A.thaliana seedling root growth.

In vitro:

Journal of Biosafety, 2011, 20 (3) :207-12.

Isolation and identification of a potential allelochemical from the invasive plant Eupatorium adenophorum[Reference: WebLink]

METHODS AND RESULTS:
The chemical structures of the purified compounds were identified by spectroscopy, including MS and NMR techniques. The allelopathic potential of sub-fractions of EtOAc extract and isolated pure compounds as well as two literature reported terpenoid allelochemicals, 8-Hydroxy-4-cadinen-3-one (2) and 4,7(11)-cadinadiene-3,8-dione (3), and signaling compound JA-Ile, were all evaluated by detecting their inhibitory activity against seeds germination and seedling root growth using Arabidopsis thaliana as test plant. A bioactive compound was isolated from one polar sub-fraction of EtOAc extract of E.adenophorum and its chemical structure was identified as 2-coumaric acid glucoside (1). Bioassay indicated that compound 1 showed significant inhibitory activity against A.thaliana seedling root growth at concentration as low as 0.1 mmol·L-1, which is more potent than the other two identified compounds. A closely similar inhibition pattern of 1 to that of the signaling compound JA-Ile were also observed.
CONCLUSIONS:
In addition to less polar terpenoids, potentially existing large polar allelochemicals in E.adenophorum might significantly contribute the total allelopathic effects. The discovery of compound 1 and other potential polar allelochemicals from E.adenophorum may significantly promote the elucidation of the potential allelopathic mechanism possessed by this well-known invasive plant.

8-Hydroxy-4-cadinen-3-one Description

Source:	The herbs of Eupatorium adenophorum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	8-Hydroxy-4-cadinen-3-one
Price:
CAS No.:	97372-53-7
Catalog No.:	CFN97550
Molecular Formula:	C₁₅H₂₄O₂
Molecular Weight:	236.4 g/mol
Purity:	>=98%
Type of Compound:	Sesquiterpenoids
Physical Desc.:	Oil
Source:	The herbs of Eupatorium adenophorum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-plant-germination and growth Compound Library Sesquiterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.2301 mL	21.1506 mL	42.3012 mL	84.6024 mL	105.753 mL
5 mM	0.846 mL	4.2301 mL	8.4602 mL	16.9205 mL	21.1506 mL
10 mM	0.423 mL	2.1151 mL	4.2301 mL	8.4602 mL	10.5753 mL
50 mM	0.0846 mL	0.423 mL	0.846 mL	1.692 mL	2.1151 mL
100 mM	0.0423 mL	0.2115 mL	0.423 mL	0.846 mL	1.0575 mL

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CFN89214	7-Hydroxycadalene	2102-75-2	214.30	C₁₅H₁₈O
CFN99070	3-Acetoxy-4,7(11)-cadinadien-8-one	104975-02-2	276.4	C₁₇H₂₄O₃
CFN97272	9-Oxo-10,11-dehydroageraphorone	79491-71-7	232.3	C₁₅H₂₀O₂
CFN96752	7alpha-Hydroxy-4,11-cadinadiene-3,8-dione	1423809-64-6	248.32	C₁₅H₂₀O₃
CFN99884	Oplopanone	1911-78-0	238.4	C₁₅H₂₆O₂
CFN90629	Tussilagone	104012-37-5	390.51	C₂₃H₃₄O₅
CFN98296	Reneilmol	260968-11-4	256.4	C₁₅H₂₈O₃
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