Science | Nature | Cell | View More
Natural Products
9-O-Feruloyl-5,5'-dimethoxylariciresinol
9-O-Feruloyl-5,5'-dimethoxylariciresinol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 9-O-Feruloyl-5,5'-dimethoxylariciresinol
Price:
CAS No.: 166322-14-1
Catalog No.: CFN99700
Molecular Formula: C32H36O11
Molecular Weight: 596.6 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The herbs of Viburnum cylindricum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Institute of Pathophysiology Me... (Austria)
  • Florida International University (USA)
  • Lodz University of Technology (Poland)
  • Monash University Sunway Campus (Malaysia)
  • Michigan State University (USA)
  • Leibniz-Institut für Pflanzenb... (Germany)
  • Kazusa DNA Research Institute (Japan)
  • Universidad Industrial de Santa... (Colombia)
  • Instituto de Investigaciones Ag... (Chile)
  • University of Bonn (Germany)
  • Centralised Purchases Unit (CPU... (India)
  • More...
Package
Featured Products
Astilbin

Catalog No: CFN98371
CAS No: 29838-67-3
Price: $30/20mg
3-oxo-Olean-12-en-28-oic acid

Catalog No: CFN92194
CAS No: 17990-42-0
Price: $90/20mg
Evodiamine

Catalog No: CFN99993
CAS No: 518-17-2
Price: $40/20mg
Hinokitiol

Catalog No: CFN93995
CAS No: 499-44-5
Price: $30/20mg
Isofraxidin

Catalog No: CFN90181
CAS No: 486-21-5
Price: $40/20mg
Sakakin

Catalog No: CFN98059
CAS No: 21082-33-7
Price: $40/20mg
Acteoside

Catalog No: CFN97048
CAS No: 61276-17-3
Price: $60/20mg
Calenduloside E

Catalog No: CFN91169
CAS No: 26020-14-4
Price: $268/10mg
Picrasidine I

Catalog No: CFN99019
CAS No: 100234-59-1
Price: $368/5mg
(+)-Isocorynoline

Catalog No: CFN90215
CAS No: 475-67-2
Price: $138/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, with ED50 values of 9.86 to approximately 12.68 microg/ml.
Targets: TNF-α | IL Receptor
In vitro:
Arch. Pharm. Res.,2014 Apr;37(4):467-72.
A new neolignan and lignans from the stems of Lindera obtusiloba Blume and their anti-allergic inflammatory effects.[Pubmed: 24014307 ]

METHODS AND RESULTS:
A new neolignan, linderin A (1), together with six known lignans, (+)-xanthoxyol (2), pluviatilol (3), actiforin (4), (+)-syringaresinol (5), (+)-(7S,8R,8'R)-acuminatolide (6), and (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol (9-O-Feruloyl-5,5'-dimethoxylariciresinol,7) were isolated from the stems of Lindera obtusiloba Blume (Lauraceae). Their chemical structures were elucidated by a combination of spectroscopic analysis and chemical reaction, and the absolute configuration of 1 was determined by Mosher's esterification. The effect of compounds 1-7 on tumor necrosis factor (TNF)-α, interleukin(IL)-6, and their inhibitory activity of histamine release were examined using human mast cells. Among the lignans tested, compounds 1, 3, 4, 6, and 7 inhibited release of histamine from mast cells. Especially, compounds 1 and 4 suppressed the gene expressions of pro-inflammatory cytokines, TNF-α, and IL-6 in human mast cells.
CONCLUSIONS:
Our findings suggest that the lignan constituents in L. obtusiloba may contribute to its anti-allergic inflammatory effects.
9-O-Feruloyl-5,5'-dimethoxylariciresinol Description
Source: The herbs of Viburnum cylindricum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Rosmarinyl glucoside

Catalog No: CFN95297
CAS No: 910028-78-3
Price: $413/5mg
(Z)-Ferulic acid 4-O-beta-D-glucos...

Catalog No: CFN95546
CAS No: 94942-20-8
Price: $318/10mg
Iristectorin A-6''-O-glucoside

Catalog No: CFN95597
CAS No: 86849-71-0
Price: $413/5mg
Caohuoside E

Catalog No: CFN95016
CAS No: 174286-23-8
Price: $318/5mg
4-Hydroxybenzoyl choline

Catalog No: CFN95158
CAS No: 5094-31-5
Price: $318/20mg
Methyl ganoderate A

Catalog No: CFN95550
CAS No: 105742-78-7
Price: $413/5mg
Methyl ganoderenate B

Catalog No: CFN95534
CAS No: N/A
Price: $413/5mg
Puerol B

Catalog No: CFN95155
CAS No: 112343-17-6
Price: $398/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6762 mL 8.3808 mL 16.7616 mL 33.5233 mL 41.9041 mL
5 mM 0.3352 mL 1.6762 mL 3.3523 mL 6.7047 mL 8.3808 mL
10 mM 0.1676 mL 0.8381 mL 1.6762 mL 3.3523 mL 4.1904 mL
50 mM 0.0335 mL 0.1676 mL 0.3352 mL 0.6705 mL 0.8381 mL
100 mM 0.0168 mL 0.0838 mL 0.1676 mL 0.3352 mL 0.419 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Arch Pharm Res. 1999 Aug;22(4):417-22.
Two new lignans from Lindera obtusiloba blume.[Pubmed: 10489885]

METHODS AND RESULTS:
Two new furanolignans (3, 5), together with three known lignans (1, 2, 4), were isolated from the stem of Lindera obtusiloba (Lauraceae). The structures of the compounds were determined as actifolin (1), pluviatilol (2), 5,6-dihydroxymatairesinol (3), (+)-syringaresinol (4), and (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol (9-O-Feruloyl-5,5'-dimethoxylariciresinol,5) on the basis of physicochemical and spectroscopic evidences.
CONCLUSIONS:
Compounds 1, 2, 3, and 5 showed cytotoxicity against a small panel of human tumor cell lines with ED50 values of 3.40 to approximately 19.27 microg/ml.
Astilbin

Catalog No: CFN98371
CAS No: 29838-67-3
Price: $30/20mg
3-oxo-Olean-12-en-28-oic acid

Catalog No: CFN92194
CAS No: 17990-42-0
Price: $90/20mg
Evodiamine

Catalog No: CFN99993
CAS No: 518-17-2
Price: $40/20mg
Hinokitiol

Catalog No: CFN93995
CAS No: 499-44-5
Price: $30/20mg
Isofraxidin

Catalog No: CFN90181
CAS No: 486-21-5
Price: $40/20mg
Sakakin

Catalog No: CFN98059
CAS No: 21082-33-7
Price: $40/20mg
Acteoside

Catalog No: CFN97048
CAS No: 61276-17-3
Price: $60/20mg
Calenduloside E

Catalog No: CFN91169
CAS No: 26020-14-4
Price: $268/10mg
Picrasidine I

Catalog No: CFN99019
CAS No: 100234-59-1
Price: $368/5mg
(+)-Isocorynoline

Catalog No: CFN90215
CAS No: 475-67-2
Price: $138/20mg
Tags: buy 9-O-Feruloyl-5,5'-dimethoxylariciresinol | 9-O-Feruloyl-5,5'-dimethoxylariciresinol supplier | purchase 9-O-Feruloyl-5,5'-dimethoxylariciresinol | 9-O-Feruloyl-5,5'-dimethoxylariciresinol cost | 9-O-Feruloyl-5,5'-dimethoxylariciresinol manufacturer | order 9-O-Feruloyl-5,5'-dimethoxylariciresinol | 9-O-Feruloyl-5,5'-dimethoxylariciresinol distributor