| Structure Identification: |
| Tetrahedron Volume 39, Issue 1, 1983, Pages 41-47 | | Steroidal alkaloids (batrachotoxins and 4β-hydroxybatrachotoxins), “indole alkaloids” (calycanthine and chimonanthine) and a piperidinyldipyridin[Reference: WebLink] |
METHODS AND RESULTS:
Skin extracts from the Colombian poison-dan frog Phytlobates terribilis contain three major steroidal alkaloids; Batrachotoxin, homobatrachotoxin and batrachotoxinin A. Minor congeners of batrachotoxin and homobalrachotoxin containing a 4β-OH substituent are identified based on mass spectra and proton and carbon-13 NMR.
CONCLUSIONS:
Two “indole alkaloids” 1-calycanthine and d-chimonanthine, enantiomeric to the same compounds from plants, and norAnabasamine (5-(2-piperidyl)2,3'-dipyridine), a des-N-Me analog of the plant alkaloid Anabasamine, are present as minor constituents. | | J Asian Nat Prod Res. 2008 Nov-Dec;10(11-12):1093-5. | | Alkaloids from Anabasis aphylla L.[Pubmed: 19031252 ] |
METHODS AND RESULTS:
A new pyridine alkaloid 1, together with three known alkaloids N-methylanabasine (2), Anabasamine (3), and isonicoteine (4), was isolated from the aerial part of Anabasis aphylla L. Their structures were elucidated by spectroscopic analysis. |
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