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Benzyl cinnamate
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Benzyl cinnamate
Price: $30 / 20mg
CAS No.: 103-41-3
Catalog No.: CFN98196
Molecular Formula: C16H14O2
Molecular Weight: 238.28 g/mol
Purity: >=98%
Type of Compound: Phenylpropanoids
Physical Desc.: Powder
Source: The barks of Cinnamomum cassia Presl
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $8.9 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Benzyl cinnamate, a flavouring agent isolated from various plant species, is used in heavy oriental perfumes and as a fixative. Benzyl cinnamate has anti-inflammatory activity, it can treat trachoma, corneal opacities, Meniere's syndrome and tinnitus aurum.
Targets: Immunology & Inflammation related
In vivo:
Harlem Hospital Bulletin, 1960, 1:97-102.
Benzyl cinnamate (Jacobson's solution) with vitamin A. A one-year experience in the treatment of cerebrovascular lesions.[Reference: WebLink]
Benzyl cinnamate (Jacobson's solution) with vitamin A. A one-year experience in the treatment of cerebrovascular lesions.
Arch. Ophthalmol., 1936, 16(3):400-4.
BENZYL CINNAMATE IN THE TREATMENT OF TRACHOMA AND CORNEAL OPACITIES.[Reference: WebLink]
In 1919 I introduced the use of Benzyl cinnamate in the treatment of tuberculosis. In order to inquire into the efficacy of this drug against tuberculosis, I used it first in the treatment of external forms of the disease, such as tuberculosis of the skin, mucous membranes and glands. These lesions being visible, it was easy to control and to follow the course of the disease. The results obtained proved worthy of interest and were confirmed by Darier and Jeanselme.1 My subsequent researches showed that the therapeutic action of the drug is not specific for tuberculosis.
CONCLUSIONS:
Its action can be seen wherever a focus of chronic inflammation is found, regardless of the nature of the agent which produces the lesion.It was by pure chance that Benzyl cinnamate found its application in the field of ophthalmology. While treating an Algerian Arab for glandular tuberculosis, I observed that while
Benzyl cinnamate Description
Source: The barks of Cinnamomum cassia Presl
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

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IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.1967 mL 20.9837 mL 41.9674 mL 83.9349 mL 104.9186 mL
5 mM 0.8393 mL 4.1967 mL 8.3935 mL 16.787 mL 20.9837 mL
10 mM 0.4197 mL 2.0984 mL 4.1967 mL 8.3935 mL 10.4919 mL
50 mM 0.0839 mL 0.4197 mL 0.8393 mL 1.6787 mL 2.0984 mL
100 mM 0.042 mL 0.2098 mL 0.4197 mL 0.8393 mL 1.0492 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Animal Research:
US4587260[P]. 1986.
Dibenzalacetone and benzyl cinnamate as non-steroidal anti-inflammatory compounds and compositions thereof[Reference: WebLink]
A non-steroidal anti-inflammatory composition comprising an active anti-inflammatory agent having the formula: ##STR1## wherein R is ##STR2## The active agent is formulated with a pharmaceutically acceptable carrier for use in the treatment of pain, inflammation and other related symptoms on mammals. Benzyl cinnamate and dibenzalacetone are preferred.
Structure Identification:
J Agric Food Chem. 2011 Jan 12;59(1):282-8.
Propolis specimens from different locations of central Italy: chemical profiling and gas chromatography-mass spectrometry (GC-MS) quantitative analysis of the allergenic esters benzyl cinnamate and benzyl salicylate.[Pubmed: 21126078]
Propolis is a beehive product popular in natural medicine thanks to its noteworthy properties. Propolis is non-toxic but is responsible for allergic reactions in sensitive individuals.
METHODS AND RESULTS:
In this paper, we propose a new gas chromatography-mass spectrometry (GC-MS) analytical methodology for the quantitative analysis of two allergenic esters in propolis specimens, benzyl salicylate and Benzyl cinnamate, and test it on specimens from different locations of central Italy. We also present the results obtained in the chemical characterization of the same specimens.
CONCLUSIONS:
The characterization showed that the resin fractions of all of the specimens are of poplar origin.
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