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Bergamotine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Bergamotine
Price: $138 / 10mg
CAS No.: 7380-40-7
Catalog No.: CFN90592
Molecular Formula: C21H22O4
Molecular Weight: 338.4 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The fruits of Citrus medica L. var. sarcodactylis Swingle
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $55.3 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Bergamotine can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-Aydiabetic mice.
Bergamotine Description
Source: The fruits of Citrus medica L. var. sarcodactylis Swingle
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9551 mL 14.7754 mL 29.5508 mL 59.1017 mL 73.8771 mL
5 mM 0.591 mL 2.9551 mL 5.9102 mL 11.8203 mL 14.7754 mL
10 mM 0.2955 mL 1.4775 mL 2.9551 mL 5.9102 mL 7.3877 mL
50 mM 0.0591 mL 0.2955 mL 0.591 mL 1.182 mL 1.4775 mL
100 mM 0.0296 mL 0.1478 mL 0.2955 mL 0.591 mL 0.7388 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Annales Des Falsifications De Lexpertise Chimique Et Toxicologique, 2000.
HPCL-control of citrus essential oils: application to lemon essential oils. [Reference: WebLink]

METHODS AND RESULTS:
La fraction non volatile des huiles essentielles de citron (Citrus limon (L.) Burm.f.) de differentes origines a ete etudiee qualitativement par CLHP en phase normale avec detection par barrettes de diodes a 313 nm. Des composes appartenant aux familles des coumarines, psoralenes et polymethoxyflavones ont ete mis en evidence. Il s' agit de la Bergamotine, de l' iso-imperatorine, du 5-geranyloxy 7-methoxycoumarine (ou same), du citroptene, du 5-isopenteniloxy 7-methoxycoumarine, de l' herniarine, du bergaptene, de l' oxypeucedanine, de l' hydrate d' oxypeucedanine et du byakangelicol. La presence d' herniarine longtemps decrite dans la litterature comme une adulteration de l' huile essentielle de citron avec de l' essence de limette (Citrus aurentifolia Christ. Swingle) est confirmee comme compose present naturellement dans la variete originaire de Cote d' Ivoire (Citrus limon (L.) var. Eureka).
CONCLUSIONS:
Enfin la methode decrite peut etre utilisee pour d' autres huiles essentielles de citrus telles que l' orange, le pamplemousse, la bergamote, la bigarade, la limette, la mandarine, la tangerine, le petitgrain citronnier ou encore le petitgrain bigaradier. D' eventuels melanges d' huiles essentielles de citron avec d' autres citrus peuvent etre mis en evidence par le suivi de composes traceurs propres a chaque huile essentielle.
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