ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
More articles cited ChemFaces products.
J Ethnopharmacol. 2017 Jan 20;Advance Publication2015 Aug 18Universidade Estadual Paulista2017-02-19Food Chem. 2017 Aug 1;Tissue and Organ Culture (PCTOC)2016 Jun 28;
Phytomedicine. 2017 Jan 15;Int J Anal Chem.2017;Anal Bioanal Chem. 2016 Jun;408(15)Int. J. of Food Properties08 Feb 2017;Phytother Res.2015 Apr 17.
Molecules. 2017 Jun 2;Aquaculture1 Dec. 2017BMC Complement Altern Med.2014 Jul 14;14:242.Evid Based Complement Alternat Med. 2017:6360836.
Our products had been exported to the following research institutions and universities, And still growing.
University of Medicine and Pharm... (Romania)Deutsches Krebsforschungszentrum (Germany)Institute of Chinese Materia Med... (China)University of Illinois (USA)
Universita' Degli Studi Di Cagli... (Italy)Institute of Bioorganic Chemistr... (Poland)Universidad Miguel Hernández (Spain)Heidelberg University (Germany)
National Hellenic Research Found... (Greece)Lund University (Sweden)VIB Department of Plant Systems ... (Belgium)
||Bursehernin has potential for development as an anti-tumor agent with an anti-proliferation, and cell cycle arrest inducing.
|J Mol Graph Model. 2017 Jun;74:215-224. |
|Structure-guided cancer blockade between bioactive bursehernin and proteins: Molecular docking and molecular dynamics study.[Pubmed: 28456097 ]|
|Bursehernin (5'-desmethoxyyatein) is a natural lignan, which has anti-tumor activity in vitro.
METHODS AND RESULTS:
In this study, the binding-inhibitory effects of Bursehernin were screening on selected 80 proteins associated with cancer pathway. The computational analysis suggested inhibitory effect due to Bursehernin towards proteins related to cancer proliferation, including FMS kinase receptor, heat shock protein 90-α (Hsp90-α), adenylate cyclase 10 (ADCY10), mitogen-activated protein kinase kinase (MEK1), and α-tubulin. Moreover, Bursehernin could interfere with cell cycle progression via binding to cyclin B proteins. Among all screened proteins, the compound showed an interesting binding affinity to the FMS kinase receptor. The binding mode studies by molecular dynamic technique showed that aromatic ring of Bursehernin compound was responsible for compound-protein interaction through pi-pi stacking with Tyr105 and Phe178 of the FMS kinase receptor.
This study suggests that Bursehernin has potential for development as an anti-tumor agent with an anti-proliferation, and cell cycle arrest inducing, although further studies are needed.
||The herbs of Macaranga tanarius
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.