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    (+)-Catechin hydrate
    Information
    CAS No. 225937-10-0 Price $40 / 20mg
    Catalog No.CFN90163Purity>=98%
    Molecular Weight308.28Type of CompoundFlavonoids
    FormulaC15H16O7Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison
    Citing Use of our Products
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $14.4 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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  • Package
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  • Biological Activity
    Description: (+)-Catechin hydrate has antioxidant activity and is effective in reducing oxidative stress. (+)-Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
    Targets: COX-1
    In vivo:
    Indian J Exp Biol. 2013 Oct;51(10):823-7.
    Effect of (+)-catechin hydrate on oxidative stress induced by high sucrose and high fat diet in male Wistar rats.[Pubmed: 24266106]

    METHODS AND RESULTS:
    Increased lipid peroxidation and reduced glutathione levels in liver of rats fed high sucrose high fat (HSHF) diet were normalized by concomitant administration of (+)-Catechin hydrate. Plasma non-enzymatic antioxidants viz. alpha-tocopherol, ascorbic acid and total thiols decrease were also significantly less in rats administered with (+)-Catechin hydrate concomitantly with HSHF diet. Thus the present results indicate that (+)-Catechin hydrate has antioxidant activity and is effective in reducing oxidative stress.
    CONCLUSIONS:
    The study is of clinical importance as oxidative stress is known to be the cause of many clinical manifestations viz. cancer, Parkinson's disease, atherosclerosis, heart failure, myocardial infarction and many other diseases.
    (+)-Catechin hydrate Description
    Source: The herbs of Camellia sinensis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.2438 mL 16.219 mL 32.438 mL 64.8761 mL 81.0951 mL
    5 mM 0.6488 mL 3.2438 mL 6.4876 mL 12.9752 mL 16.219 mL
    10 mM 0.3244 mL 1.6219 mL 3.2438 mL 6.4876 mL 8.1095 mL
    50 mM 0.0649 mL 0.3244 mL 0.6488 mL 1.2975 mL 1.6219 mL
    100 mM 0.0324 mL 0.1622 mL 0.3244 mL 0.6488 mL 0.811 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.