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    Cerebroside B
    Cerebroside B
    Information
    CAS No. 88642-46-0 Price
    Catalog No.CFN97455Purity>=98%
    Molecular Weight728.1 Type of CompoundCerebrosides
    FormulaC41H77NO9Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)
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    Our products had been exported to the following research institutions and universities, And still growing.
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    Cerebroside B Description
    Source: From Boletus calopus
    Biological Activity or Inhibitors: 1.Cerebroside B1b has antiulcerogenic activity.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.3734 mL 6.8672 mL 13.7344 mL 27.4688 mL 34.3359 mL
    5 mM 0.2747 mL 1.3734 mL 2.7469 mL 5.4938 mL 6.8672 mL
    10 mM 0.1373 mL 0.6867 mL 1.3734 mL 2.7469 mL 3.4336 mL
    50 mM 0.0275 mL 0.1373 mL 0.2747 mL 0.5494 mL 0.6867 mL
    100 mM 0.0137 mL 0.0687 mL 0.1373 mL 0.2747 mL 0.3434 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Cerebroside B References Information
    Citation [1]

    Sci Rep. 2015 May 21;5:10486.

    Δ10(E)-Sphingolipid Desaturase Involved in Fusaruside Mycosynthesis and Stress Adaptation in Fusarium graminearum.[Pubmed: 25994332]
    Heterologous expression of Δ10(E)-SD in Pichia pastoris has been established to facilitate a reliable generation of 1 through the Δ10(E)-SD catalyzed desaturation of Cerebroside B (2), an abundant fungal sphingolipid. Site directed mutageneses show that the conserved histidines of Δ10(E)-SD are essential for the 10,11-desaturation catalysis, which is also preconditioned by the C9-methylation of the substrate. Moreover, Δ10(E)-SD confers improved survival and faster growth to fungal strains at low temperature and high salinity, in parallel with to higher contents of 1 in the mycelia.
    Citation [2]

    Nat Prod Res. 2013;27(1):80-4.

    Steroids and phenolic constituents from the fruiting bodies of the basidiomycete Sarcodon joedes.[Pubmed: 22320163]
    Nine secondary metabolites, including four steroids, four phenolics and one cerebroside, were isolated from the methanol extract of the fruiting bodies of the basidiomycete Sarcodon joedes. The isolated compounds were identified by spectroscopic analyses as (22E,24R)-6β-methoxyergosta-7,22-diene-3β,5α-diol (1), 2',3'-diacetoxy-3,4,5',6',4″-pentahydroxy-p-terphenyl (2), Cerebroside B (3), ergosta-7,22-dien-3β-ol (4), ergosterol peroxide (5), (22E,24R)-3β-hydroxy-ergosta-5,22-dien-7-one (6), benzoic acid (7), methyl p-hydroxybenzoate (8) and 3,4-dihydroxybenzoic acid (9). The cytotoxic activities of these compounds were evaluated. All these compounds were isolated from this fungus for the first time.
    Citation [3]

    Tetrahedron, 1989, 45(23):7263-80.

    Synthesis of cerebroside B1b with antiulcerogenic activity I. Synthesis of ceramides with optically active α-hydroxypalmitic acids.[Reference: WebLink]
    Synthesis of Cerebroside B1b with antiulcerogenic activity I. Synthesis of ceramides with optically active α-hydroxypalmitic acids.