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    Coniferyl alcohol
    Coniferyl alcohol
    Information
    CAS No. 32811-40-8 Price $268 / 10mg
    Catalog No.CFN97760Purity>=98%
    Molecular Weight180.20Type of CompoundPhenylpropanoids
    FormulaC10H12O3Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: Coniferyl alcohol restores the growth of KI-treated BY-2 cells and N. benthamiana seedlings, at high concentrations is toxic to plant cells.
    In vitro:
    Planta. 2015 Jun 25.
    Coniferyl alcohol hinders the growth of tobacco BY-2 cells and Nicotiana benthamiana seedlings.[Pubmed: 26108783]
    Externally added Coniferyl alcohol at high concentrations reduces the growth of Nicotiana cells and seedlings. Coniferyl alcohol is metabolized by BY-2 cells to several compounds. Coniferyl alcohol (CA) is a common monolignol and a building block of lignin. The toxicity of monolignol alcohols has been stated in the literature, but there are only few studies suggesting that this is true.
    METHODS AND RESULTS:
    We investigated the physiological effects of Coniferyl alcohol on living plant cells in more detail. Tobacco (Nicotiana tabacum) Bright yellow-2 cells (BY-2) and Nicotiana benthamiana seedlings both showed concentration-dependent growth retardation in response to 0.5-5 mM Coniferyl alcohol treatment. In some cases, Coniferyl alcohol addition caused cell death in BY-2 cultures, but this response was dependent on the growth stage of the cells. Based on LC-MS/MS analysis, BY-2 cells did not accumulate the externally supplemented Coniferyl alcohol, but metabolized it to ferulic acid, ferulic acid glycoside, coniferin, and to some other phenolic compounds. In addition to growth inhibition, Coniferyl alcohol caused the formation of a lignin-like compound detected by phloroglucinol staining in N. benthamiana roots and occasionally in BY-2 cells. To prevent this, we added potassium iodide (KI, at 5 mM) to overcome the peroxidase-mediated Coniferyl alcohol polymerization to lignin. KI had, however, toxic effects on its own: in N. benthamiana seedlings, it caused reduction in growth; in BY-2 cells, reduction in growth and cell viability. Surprisingly, Coniferyl alcohol restored the growth of KI-treated BY-2 cells and N. benthamiana seedlings.
    CONCLUSIONS:
    Our results suggest that Coniferyl alcohol at high concentrations is toxic to plant cells.
    Coniferyl alcohol Description
    Source: The herbs of Acanthopanax gracilistylus
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.5494 mL 27.7469 mL 55.4939 mL 110.9878 mL 138.7347 mL
    5 mM 1.1099 mL 5.5494 mL 11.0988 mL 22.1976 mL 27.7469 mL
    10 mM 0.5549 mL 2.7747 mL 5.5494 mL 11.0988 mL 13.8735 mL
    50 mM 0.111 mL 0.5549 mL 1.1099 mL 2.2198 mL 2.7747 mL
    100 mM 0.0555 mL 0.2775 mL 0.5549 mL 1.1099 mL 1.3873 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.