ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Int J Biol Macromol. 2018 Feb 12. Int. Conference on Med. Sci. and Bio.2017;Int J Mol Sci.2015 Aug 7;16(8):18396-411.?New Zealand Journal of Forestry Sci.2014, 44:17Korean J. of Food Sci. and TechApril 2016
J Basic Clin Physiol Pharmacol.2015 Aug 15J Nat Med.2017 Jul 5. Nat Prod Sci.2016 Jun;22(2)Acta ChromatographicaOct. 11, 2016Scientific ResearchJune 20, 2017
J Nat Med.2017 AprActa Physiologiae Plantarum.2014 10.J Ethnopharmacol. 2016 Jul 12.Molecules.2013 Jun 24;18(7):7376-88.
Our products had been exported to the following research institutions and universities, And still growing.
Regional Crop Research Institute (Korea)Weizmann Institute of Science (Israel)Ain Shams University (Egypt)The Vancouver Prostate Centre (V... (Canada)
University Medical Center Mainz (Germany)University of Zurich (Switzerland)Monash University (Australia)University of Auckland (New Zealand)
Medical University of Gdansk (Poland)University of Minnesota (USA)Kazusa DNA Research Institute (Japan)
|| Coniferyl alcohol restores the growth of KI-treated BY-2 cells and N. benthamiana seedlings, at high concentrations is toxic to plant cells.|
|Planta. 2015 Jun 25. |
|Coniferyl alcohol hinders the growth of tobacco BY-2 cells and Nicotiana benthamiana seedlings.[Pubmed: 26108783]|
|Externally added Coniferyl alcohol at high concentrations reduces the growth of Nicotiana cells and seedlings. Coniferyl alcohol is metabolized by BY-2 cells to several compounds. Coniferyl alcohol (CA) is a common monolignol and a building block of lignin. The toxicity of monolignol alcohols has been stated in the literature, but there are only few studies suggesting that this is true. |
METHODS AND RESULTS:
We investigated the physiological effects of Coniferyl alcohol on living plant cells in more detail. Tobacco (Nicotiana tabacum) Bright yellow-2 cells (BY-2) and Nicotiana benthamiana seedlings both showed concentration-dependent growth retardation in response to 0.5-5 mM Coniferyl alcohol treatment. In some cases, Coniferyl alcohol addition caused cell death in BY-2 cultures, but this response was dependent on the growth stage of the cells. Based on LC-MS/MS analysis, BY-2 cells did not accumulate the externally supplemented Coniferyl alcohol, but metabolized it to ferulic acid, ferulic acid glycoside, coniferin, and to some other phenolic compounds. In addition to growth inhibition, Coniferyl alcohol caused the formation of a lignin-like compound detected by phloroglucinol staining in N. benthamiana roots and occasionally in BY-2 cells. To prevent this, we added potassium iodide (KI, at 5 mM) to overcome the peroxidase-mediated Coniferyl alcohol polymerization to lignin. KI had, however, toxic effects on its own: in N. benthamiana seedlings, it caused reduction in growth; in BY-2 cells, reduction in growth and cell viability. Surprisingly, Coniferyl alcohol restored the growth of KI-treated BY-2 cells and N. benthamiana seedlings.
Our results suggest that Coniferyl alcohol at high concentrations is toxic to plant cells.
Coniferyl alcohol Description
||The herbs of Acanthopanax gracilistylus
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.