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Cucurbitacin S
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Product Name Cucurbitacin S
Price:
CAS No.: 60137-06-6
Catalog No.: CFN90535
Molecular Formula: C30H42O6
Molecular Weight: 498.65 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The rhizomes of Hemsleya amabilis Diels.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities.
Targets: Immunology & Inflammation related
Cucurbitacin S Description
Source: The rhizomes of Hemsleya amabilis Diels.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
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ACS Nano. 2018 Apr 24;12(4): 3385-3396.
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IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
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IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0054 mL 10.0271 mL 20.0541 mL 40.1083 mL 50.1354 mL
5 mM 0.4011 mL 2.0054 mL 4.0108 mL 8.0217 mL 10.0271 mL
10 mM 0.2005 mL 1.0027 mL 2.0054 mL 4.0108 mL 5.0135 mL
50 mM 0.0401 mL 0.2005 mL 0.4011 mL 0.8022 mL 1.0027 mL
100 mM 0.0201 mL 0.1003 mL 0.2005 mL 0.4011 mL 0.5014 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry Volume 21, Issue 11, 1982, Pages 2703–2707
A revision of the structure of cucurbitacin S from Bryonia dioica[Reference: WebLink]
1H NMR studies at 400 MHz on Cucurbitacin S and its derivatives suggest that the structure of Cucurbitacin S previously isolated from Bryonia dioica should be revised from (22S)-22, 25-anhydro-2,16α,22,25-tetrahydroxy-3,11,23-trioxo-cucurbita-1,5-diene to (24S)-16,24-anhydro- 2,16α,24,25-tetrahydroxy-3,11,22-trioxo-cucurbita-1,5-diene.
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