Daphnilongeridine | CAS:922522-15-4 | Manufacturer ChemFaces

Daphnilongeridine

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Daphnilongeridine shows cytotoxicity against several tumor cell lines.

In vitro:

J Nat Prod. 2009 Sep;72(9):1669-72.

Alkaloids from the leaves of Daphniphyllum subverticillatum.[Pubmed: 19739650]

METHODS AND RESULTS:
Four new alkaloids, 17-hydroxydaphnigraciline (1), subdaphnidine A (2), daphnezomine L methyl ester (3), and 11-hydroxycodaphniphylline (4), along with 24 known analogues, were isolated from the leaves of Daphniphyllum subverticillatum. The structures of 1-4 were elucidated on the basis of spectroscopic methods and from chemical evidence.
CONCLUSIONS:
Daphnilongeridine (5) showed cytotoxicity against several tumor cell lines at IC(50) values in the range 2.4-9.7 microM and against the HMEC human microvascular endothelial cell line with an IC(50) of 2.7 microM.

Daphnilongeridine Description

Source:	The branches of Daphniphyllum macropodum Miq.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Daphnilongeridine
Price:
CAS No.:	922522-15-4
Catalog No.:	CFN97484
Molecular Formula:	C₃₂H₅₁NO₄
Molecular Weight:	513.8 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The branches of Daphniphyllum macropodum Miq.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.9463 mL	9.7314 mL	19.4628 mL	38.9257 mL	48.6571 mL
5 mM	0.3893 mL	1.9463 mL	3.8926 mL	7.7851 mL	9.7314 mL
10 mM	0.1946 mL	0.9731 mL	1.9463 mL	3.8926 mL	4.8657 mL
50 mM	0.0389 mL	0.1946 mL	0.3893 mL	0.7785 mL	0.9731 mL
100 mM	0.0195 mL	0.0973 mL	0.1946 mL	0.3893 mL	0.4866 mL

CFN97484	Daphnilongeridine	922522-15-4	513.8	C₃₂H₅₁NO₄
CFN98003	Daphmacrine	19775-48-5	511.8	C₃₂H₄₉NO₄
CFN98270	Daphnezomine B	247078-43-9	375.6	C₂₃H₃₇NO₃
CFN98629	Daphmacropodine	39729-21-0	513.8	C₃₂H₅₁NO₄
CFN99061	Yunnandaphninine G	1042143-83-8	469.7	C₃₀H₄₇NO₃
CFN99284	11-Hydroxycodaphniphylline	1186496-68-3	485.7	C₃₀H₄₇NO₄
CFN99608	Codaphniphylline	14694-15-6	469.7	C₃₀H₄₇NO₃