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Delgrandine
Delgrandine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Delgrandine
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CAS No.: 145237-05-4
Catalog No.: CFN89550
Molecular Formula: C41H43NO12
Molecular Weight: 741.77 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Delphinium davidii
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Reference standards.
Delgrandine Description
Source: The herbs of Delphinium davidii
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3481 mL 6.7406 mL 13.4813 mL 26.9625 mL 33.7032 mL
5 mM 0.2696 mL 1.3481 mL 2.6963 mL 5.3925 mL 6.7406 mL
10 mM 0.1348 mL 0.6741 mL 1.3481 mL 2.6963 mL 3.3703 mL
50 mM 0.027 mL 0.1348 mL 0.2696 mL 0.5393 mL 0.6741 mL
100 mM 0.0135 mL 0.0674 mL 0.1348 mL 0.2696 mL 0.337 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Acta Chimica Sinica, 1992, 50(08):822-826.
The Alkaloidal Constituents of Delphinium grandiflorum L[J].[Reference: WebLink]

METHODS AND RESULTS:
The structures of Delgrandine (1) and acetylDelgrandine (2), isolated as minor constituents from the roots of Delphinium grandiflorum L., have been inferred from the spectroscopic analysis, especially the ~(13)C-~1H COSY, ~1H-~1H COSY and two dimensional NOE spectrum.
CONCLUSIONS:
1 and 2 are two rare examples among the C_(20) diterpenoid alkaloids reported so far in the sense that they are the most highly substituted with hydroxy or acetyloxy or benzoyloxy groups and characterized by having an aldehyde group at 4-c.
CFN90228Bullatine A1354-84-3343.51C22H33NO2
CFN93074Karacoline39089-30-0377.52C22H35NO4
CFN91495Guan-fu base A1394-48-5429.5C24H31NO6
CFN89550Delgrandine145237-05-4741.77C41H43NO12
CFN8954714-Dehydrodelcosine1361-18-8451.55C24H37NO7
CFN99502Acoforestinine110011-77-3645.79C35H51NO10
CFN893298-Deacetylyunaconitine93460-55-0617.73C33H47NO10
CFN99503Yunaconitine70578-24-4659.77C35H49NO11
CFN893623-Acetylyunaconitine80787-51-5701.80C37H51NO12
CFN99720Bulleyaconitine A107668-79-1643.8C35H49NO10
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