Desmethoxycentaureidin | CAS:22934-99-2

Desmethoxycentaureidin

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Description:

Desmethoxycentaureidin shows high inhibitory activity against HeLa cell growth (GI50 9 microM).

In vitro:

Biol Pharm Bull. 2002 Jul;25(7):920-2.

Antiproliferative constituents in plants 9. Aerial parts of Lippia dulcis and Lippia canescens.[Pubmed: 12132670]

Three flavones [Desmethoxycentaureidin (10), eupafolin (11), and 6-hydroxyluteolin (12)] from the latter.
METHODS AND RESULTS:
Antiproliferative activity of the isolated compounds against murine melanoma (B16F10), human gastric adenocarcinoma (MK-1), and human uterine carcinoma (HeLa) cells was estimated. (+)-Anymol (3), acteoside (4), isoacteoside (5), arenarioside (8), eupafolin (11), and 6-hydroxyluteolin (12) had GI50 values of 10-16 microM against B16F10 cell. Desmethoxycentaureidin (10) and eupafolin (11) showed high inhibitory activity against HeLa cell growth (GI50 9 microM, and 6 microM, respectively).

Desmethoxycentaureidin Description

Source:	The herbs of Lippia dulcis Trev.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Desmethoxycentaureidin
Price:
CAS No.:	22934-99-2
Catalog No.:	CFN98234
Molecular Formula:	C₁₇H₁₄O₇
Molecular Weight:	330.3 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Yeollow powder
Source:	The herbs of Lippia dulcis Trev.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-proliferation Compound Library Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.0276 mL	15.1378 mL	30.2755 mL	60.551 mL	75.6888 mL
5 mM	0.6055 mL	3.0276 mL	6.0551 mL	12.1102 mL	15.1378 mL
10 mM	0.3028 mL	1.5138 mL	3.0276 mL	6.0551 mL	7.5689 mL
50 mM	0.0606 mL	0.3028 mL	0.6055 mL	1.211 mL	1.5138 mL
100 mM	0.0303 mL	0.1514 mL	0.3028 mL	0.6055 mL	0.7569 mL

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CFN98290	Velutin	25739-41-7	314.3	C₁₇H₁₄O₆
CFN95398	4'-Hydroxy-5,7,3'-trimethoxyflavone	1239-68-5	328.3	C₁₈H₁₆O₆
CFN90386	Jaceosidin	18085-97-7	330.29	C₁₇H₁₄O₇
CFN90418	Cirsilineol	41365-32-6	344.32	C₁₈H₁₆O₇
CFN70278	Gossypetin 3,3',8-trimethylether	14965-08-3	360.3	C₁₈H₁₆O₈
CFN92436	Isothymonin	99615-01-7	360.3	C₁₈H₁₆O₈
CFN98361	5-Hydroxy-3',4',7-trimethoxyflavone	29080-58-8	328.3	C₁₈H₁₆O₆
CFN90190	Eupatilin	22368-21-4	344.31	C₁₈H₁₆O₇
CFN95415	5-Demethylsinensetin	21763-80-4	358.34	C₁₉H₁₈O₇